radical-scavenging activity of thiols, thiobarbituric acid derivatives and phenolic antioxidants determined using the induction period method for radical polymerization of methyl methacrylate自由基清除活性硫醇、硫代巴比土酸衍生品和酚类抗氧化剂决定使用诱导期自由基聚合的甲基丙烯酸甲酯的方法.pdfVIP

Polymers 2012, 4, 1025-1036; doi:10.3390/polym4021025 OPEN ACCESS polymers ISSN 2073-4360 /journal/polymers Article Radical-Scavenging Activity of Thiols, Thiobarbituric Acid Derivatives and Phenolic Antioxidants Determined Using the Induction Period Method for Radical Polymerization of Methyl Methacrylate Yoshinori Kadoma 1,* and Seiichiro Fujisawa 2 1 Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, Japan 2 Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan; E-Mail: fujisawa33@ * Author to whom correspondence should be addressed; E-Mail: y-kadoma.fm@tmd.ac.jp; Tel.: +81-3-5280-8030; Fax: +81-3-5280-8005. Received: 27 February 2012; in revised form: 2 April 2012 / Accepted: 5 April 2012 / Published: 16 April 2012 Abstract: The radical-scavenging activities of two thiols, eight (thio)barbituric acid derivatives and six chain-breaking phenolic antioxidants were investigated using the induction period method for polymerization of methyl methacrylate (MMA) initiated by thermal decomposition of 2,2 ’-azobisisobutyronitrile (AIBN) and monitored by differential scanning calorimetry (DSC). The induction period (IP) for the thiols 2-mercaptoethanol (ME) and 2-mercapto-1-methylimidazole (MMI) was about half that for phenolic antioxidants. Except for the potent inhibitor 5,5-dimethyl-2-thiobarbituric acid (3), the IP for thiobarbituric a