renal co-morbidity in patients with rheumatic diseases肾患者伴随疾病风湿性疾病.pdfVIP

Anders and Vielhauer Arthritis Research Therapy 2011, 13:222 /content/13/3/222 R E V I E W Renal co-morbidity in patients with rheumatic diseases Hans-Joachim Anders* and Volker Vielhauer How to diagnose and monitor renal co-morbidity? Abstract Renal co-morbidity may not be apparent in terms of signs Renal co-morbidity is common in patients with and symptoms, so functional parameters must be routinely rheumatic disease based on regular assessment measured. Serum creatinine is the most commonly used of serum and urine parameters of renal function. parameter for renal excretory function and is therefore When patients present with both arthritis and renal used to predict the GFR; for example, by applying the abnormalities the following questions have to Modifi cation of Diet in Renal Disease formula. Nowa- be addressed. Is kidney disease a complication of days, the estimated GFR defi nes the stage of chronic rheumatic disease or its management, or are they kidney disease (CKD) and most laboratories routinely both manifestations of a single systemic autoimmune report the estimated GFR along with serum creatinine disease? Is rheumatic disease a complication of kidney results [2]. h e Modifi cation of Diet in Renal Disease disease and its management? How do rheumatic formula as well as other formulas used for GFR predic- disease and kidney disease af ect each other even tion, however,