research and application of marine microbial enzymes status and prospects海洋微生物酶的研究和应用现状和前景.pdfVIP

Mar. Drugs 2010, 8, 1920-1934; doi:10.3390/md8061920 OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Review Research and Application of Marine Microbial Enzymes: Status and Prospects Chen Zhang 1,2 and Se-Kwon Kim 1,3,* 1 Department of Chemistry, Pukyong National University, Busan, 608-737, Korea 2 Key laboratory of Molecular Enzymology and Enzyme Engineering of Ministry Education, Jilin University, Changchun, 130023, China; E-Mail: ahxczc@ 3 Marine Bioprocess Research Center, Pukyong National University, Busan, 608-737, Korea * Author to whom correspondence should be addressed; E-Mail: sknkim@pknu.ac.kr; Tel.: +82-51-629-7097; Fax: +82-51-629-7099. Received: 10 May 2010; in revised form: 15 June 2010 / Accepted: 22 June 2010 / Published: 23 June 2010 Abstract: Over billions of years, the ocean has been regarded as the origin of life on Earth. The ocean includes the largest range of habitats, hosting the most life-forms. Competition amongst microorganisms for space and nutrients in the marine environment is a powerful selective force, which has led to evolution. The evolution prompted the marine microorganisms to generate multifarious enzyme systems to adapt to the complicated marine environments. Therefore, marine microbial enzymes can offer novel biocatalysts with extraordinary properties. This review deals with the research and development work investigating the occurrence and bioprocessing of marine microbial enzymes. Keywords: marine microbial enzymes; protease; lipase;