roles of nitric oxide and asymmetric dimethylarginine in pregnancy and fetal programming一氧化氮的作用和非对称dimethylarginine妊娠和胎儿编程.pdfVIP
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roles of nitric oxide and asymmetric dimethylarginine in pregnancy and fetal programming一氧化氮的作用和非对称dimethylarginine妊娠和胎儿编程
Int. J. Mol. Sci. 2012, 13, 14606-14622; doi:10.3390/ijms131114606
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Review
Roles of Nitric Oxide and Asymmetric Dimethylarginine in
Pregnancy and Fetal Programming
Li-Tung Huang 1,2,†, Chih-Sung Hsieh 3,4,†, Kow-Aung Chang 5 and You-Lin Tain 1,6,*
1 Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University
College of Medicine, Kaohsiung 800, Taiwan; E-Mail: huang_li@.tw
2 Department of Traditional Chinese Medicine, Chang Gung University, Linkow 333, Taiwan
3 Department of Pediatric Surgery, Pingtung Christian Hospital, Pingtung 900, Taiwan;
E-Mail: yenmeichang@.tw
4 Department of Nursing, MeiHo University, Pingtung 900, Taiwan
5 Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University
College of Medicine, Kaohsiung 800, Taiwan; E-Mail: kowaung@
6 Center for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital,
Chang Gung University College of Medicine, Kaohsiung 800, Taiwan
† These authors contributed equally to this work.
* Author to whom correspondence should be addressed; E-Mail: tainyl@;
Tel.: +886-975056995; Fax: +886-7-7338009.
Received: 12 July 2012; in revised form: 17 October 2012 / Accepted: 7 November 2012 /
Published: 9 November 2012
Abstract: Nitric oxide (NO) regulates placental blood flow and actively participates in
trophoblast invasion and placental
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