salivary proteins associated with periodontitis in patients with type 2 diabetes mellitus唾液蛋白质与2型糖尿病患者牙周炎有关.pdfVIP

Int. J. Mol. Sci. 2012, 13, 4642-4654; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Salivary Proteins Associated with Periodontitis in Patients with Type 2 Diabetes Mellitus Hang Haw Chan 1, Zubaidah H. A. Rahim 1,*, Kala Jessie 1, Onn H. Hashim 2,3 and 4 Tara B. Taiyeb-Ali 1 Department of Oral Biology, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia; E-Mails: chanhh0110@ (H.H.C.); jessiekala7@ (K.J.) 2 Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia; E-Mail: onnhashim@.my 3 University of Malaya Centre for Proteomics Research, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia 4 Department of Oral Pathology and Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia; E-Mail: tara@.my * Author to whom correspondence should be addressed; E-Mail: zubaidar@.my; Tel.: +603 Fax: +603 Received: 20 January 2012; in revised form: 23 March 2012 / Accepted: 31 March 2012 / Published: 12 April 2012 Abstract: The objective of this study was to investigate the salivary proteins that are associated with periodontitis in patients with Type 2 diabetes mellitus (T2DM). Volunteers for the study were patients from the Diabetic Unit, University of Malaya Medical Centre, whos