sdia, an n-acylhomoserine lactone receptor, becomes active during the transit of salmonella enterica through the gastrointestinal tract of turtlessdia,n-acylhomoserine内酯受体,在运输过程中变得活跃的沙门氏菌通过胃肠道的海龟.pdfVIP

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sdia, an n-acylhomoserine lactone receptor, becomes active during the transit of salmonella enterica through the gastrointestinal tract of turtlessdia,n-acylhomoserine内酯受体,在运输过程中变得活跃的沙门氏菌通过胃肠道的海龟.pdf

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sdia, an n-acylhomoserine lactone receptor, becomes active during the transit of salmonella enterica through the gastrointestinal tract of turtlessdia,n-acylhomoserine内酯受体,在运输过程中变得活跃的沙门氏菌通过胃肠道的海龟

SdiA, an N-Acylhomoserine Lactone Receptor, Becomes Active during the Transit of Salmonella enterica through the Gastrointestinal Tract of Turtles 1. 1. 1 2¤a 3¤b Jenee N. Smith , Jessica L. Dyszel , Jitesh A. Soares , Craig D. Ellermeier , Craig Altier , Sara D. 4 4 5¤d 5¤c 2 1 Lawhon , L. Garry Adams , Vjollca Konjufca , Roy Curtiss III , James M. Slauch , Brian M. M. Ahmer * 1 Department of Microbiology, The Ohio State University, Columbus, Ohio, United States of America, 2 Department of Microbiology and College of Medicine, University of Illinois, Urbana, Illinois, United States of America, 3 Department of Population Health and Pathobiology, North Carolina State University, Raleigh, North Carolina, United States of America, 4 Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas AM University, College Station, Texas, United States of America, 5 Department of Biology, Washington University, St. Louis, Missouri, United States of America Abstract Background: LuxR-type transcription factors are typically used by bacteria to determine the population density of their own species by detecting N-acylhomoserine lactones (AHLs). However, while Escherichia and Salmonella encode a LuxR-type AHL receptor, SdiA, they cannot synthesize AHLs. In vitro, it is known that SdiA can detect AHLs produced by other bacterial species. Methodology/Principal Findings: In this report, we tested the hypothesis that SdiA detects the AHL-production of other bacterial species within the animal host. SdiA did