selection for large and small litter size of the first three litters in mice选择大型和小型垃圾前三个老鼠窝的大小.pdfVIP

Selection for large and small litter size of the first three litters in mice L.F. de la FUENTE F. SAN PRIMITIVO Departamento de Genética. Facultad de Veterinaria. Universidad de Le6n. Le6n, Spain Summary A selection experiment based on female performance in 2 lines, L+ for increased and L- for decreased total number of young born alive in the first 3 births (TNY-3) was conducted for 8 generations. Line C, served as an unselected control. All litters were standardized to 8 mice. Responses and correlated responses were measured as a deviation from the control line. Heritability estimates for TNY-3 were 0.24 ± 0.10 from twice the dam-daughter regression and 0.13 ± 0.15 from the interclass correlations among half-sib families. After 8 generations of selection, the cumulated response was 3.80 young in the L+ line and -3.44 in the L- line. Realized heritabilities for TNY-3 were 0.28 ± 0.05 in the L+ line, 0.21 ±0.05 in L- line and 0.24 ±0.03 for divergence. Realized genetic correlations were 0.82 ± 0.08 between TNY-3 and first litter size, 0.50:!:! 0.12 between TNY-3 and second litter size and 0.60:!: 0.11 between TNY-3 and third litter size. Correlated responses per generation were 0.12 ± 0.07 g and - 0.22 ± 0.13 g for 6 week body weight in the L+ and L- lines respectively. Realized genetic correlations were 0.50 ± 0.13 between TNY-3 and 3-week body weight and 0.65 ± 0.04 between TNY-3 and 6-week body weight. Key words : Mice, litter size, selection, heritability. Résumé Sélection divergente sur la prolificité chez la souris à partir des résultats des trois premières mises bas Cette étude concerne une e