selection on testis size as an indicator of maturity in growing animals. i direct and correlated responses in growth在睾丸的大小作为成熟度的指标选择越来越多的动物。.pdfVIP
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selection on testis size as an indicator of maturity in growing animals. i direct and correlated responses in growth在睾丸的大小作为成熟度的指标选择越来越多的动物。
Original article
Selection on testis size as an indicator
of maturity in growing animals.
I Direct and correlated
responses
in growth
WG Hill1 PJ Marks JC Jenkins1RB Land2
Institute1
of Animal Genetics, University of Edinburgh,
West Mains- Road, Edinburgh EH9 3JN;
AFRC2Institute of Animal Physiology and Genetics Research,
Edinburgh Research Station, Roslin, Midlothian EH25 9PS, UK*
(Received 2 October 1989; accepted 15 February 1990)
Summary - Selection was undertaken in mice to test whether gonad size, specifically testis
weight, could be used to indicate degree of maturity and produce genetic change in the
shape of the growth curve from records on young animals only. Selection was practised
for 11 generations high and low on 5 wk male body weight (lines HX, LX), on 5 wk testis
weight (XH,XL) and on indices with these traits selected in the same (HH,LL) and in
opposite (HL,LH) directions. There were 2 replicates of each selection line and 4 unselected
controls. Divergences between high and low lines within family standard deviation units
for 5 wk body weight and testis weight, respectively, were: HX-LX: 1.8 and 2.3, XH-XL:
2.2 and 4.2, HH-LL: 1.9 and 3.4, and HL-LH, 2.0 and -2.7. There were minor changes
in shape of the growth curve in the direction expected, with those selected for high testis
weight showing earlier maturity. A simple measure, 6 wk weight/15 wk weight (%), for
entire males was: HX 74.3, LX 67.3, XH 71.8, XL 69.6, HH 78.1, LL 72.6, HL 74.2, LH 78.5,
averaging 76.1 for lines selected for high testis weight and 72.1 for low, compared to 74.0
for controls. In castrate males, a similar pattern of changes in growth curve was observed
indicating that they were
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