self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in gabonese childrenself-reactivities non-erythroidα的血影蛋白与脑型疟疾在加蓬的孩子.pdfVIP
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self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in gabonese childrenself-reactivities non-erythroidα的血影蛋白与脑型疟疾在加蓬的孩子
Self-Reactivities to the Non-Erythroid Alpha Spectrin
Correlate with Cerebral Malaria in Gabonese Children
1,2. 1,3. 3 4 5 1 6
Vincent Guiyedi , Youri Chanseaud , Constantin Fesel , Georges Snounou , Jean-Claude Rousselle , Pharat Lim , Jean Koko ,
5 ´ 1 2 1,2,3
Abdelkader Namane , Pierre-Andre Cazenave , Maryvonne Kombila , Sylviane Pied *
´ ´ ´
1 Unite d’Immunophysiopathologie Infectieuse, URA CNRS 1961, Universite Pierre et Marie Curie Paris, Institut Pasteur, Paris, France, 2 Departement
´ ´ ´ ´ ´
de Parasitologie-Mycologie-Medecine Tropicale, Faculte de Medecine, Universite des Sciences de la Sante, Libreville, Gabon, 3 Instituto Gulbenkian de
ˆ ´ ` ´ ´ ´ ´
Ciencia, Oeiras, Portugal, 4 Parasitologie comparee et Modeles experimentaux, Departement Ecologie et Gestion de la Biodiversite, Museum National
´ ´ ˆ ´
d’Histoire Naturelle, Paris, France, 5 Plate-Forme de Proteomique, Pasteur Genopole, Institut Pasteur, Paris, France, 6 Hopital Pediatrique d’Owendo,
Libreville, Gabon
Background. Hypergammaglobulinemia and polyclonal B-cell activation commonly occur in Plasmodium sp. infections. Some
of the antibodies pro
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