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study protocol. a prospective cohort study of unselected primiparous women the pregnancy outcome prediction study研究协议。.pdf

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study protocol. a prospective cohort study of unselected primiparous women the pregnancy outcome prediction study研究协议。

BMC Pregnancy and Childbirth BioMed Central Study protocol Open Access Study protocol. A prospective cohort study of unselected primiparous women: the pregnancy outcome prediction study 1 1 1 Dharmintra Pasupathy , Alison Dacey , Emma Cook , D Stephen Charnock- 1 2 1 Jones , Ian R White and Gordon CS Smith* Address: 1Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK and 2MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK Email: Dharmintra Pasupathy - dp349@cam.ac.uk; Alison Dacey - ad507@cam.ac.uk; Emma Cook - ec518@cam.ac.uk; D Stephen Charnock- Jones - dscj1@cam.ac.uk; Ian R White - ian.white@mrc-bsu.cam.ac.uk; Gordon CS Smith* - gcss2@cam.ac.uk * Corresponding author Published: 19 November 2008 Received: 7 August 2008 Accepted: 19 November 2008 BMC Pregnancy and Childbirth 2008, 8:51 doi:10.1186/1471-2393-8-51 This article is available from: /1471-2393/8/51 © 2008 Pasupathy et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: There have been dramatic changes in the approach to screening for aneuploidy over the last 20 years. However, the approach to screening for other complications of pregnancy su