tannins, peptic ulcers and related mechanisms单宁、消化性溃疡及相关机制.pdfVIP

Int. J. Mol. Sci. 2012, 13, 3203-3228; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Review Tannins, Peptic Ulcers and Related Mechanisms Neyres Zinia Taveira de Jesus, Heloina de Souza Falcão, Isis Fernandes Gomes, Thiago Jose de Almeida Leite, Gedson Rodrigues de Morais Lima, Jose Maria Barbosa-Filho, Josean Fechine Tavares, Marcelo Sobral da Silva, Petrônio Filgueiras de Athayde-Filho and Leonia Maria Batista * Department of Pharmaceutical Sciences, Federal University of Paraiba, João Pessoa 58051-970, PB, Brazil; E-Mails: neyresj@ (N.Z.T.J.); heloinafalcao@.br (H.S.F.); isisfarmacia@ (I.F.G.); thiago454@.br (T.J.A.L.); gedson@ltf.ufpb.br (G.R.M.L.); jbarbosa@ltf.ufpb.br (J.M.B.-F.); josean@ltf.ufpb.br (J.F.T.); marcelosobral@ltf.ufpb.br (M.S.S.); athayde-filho@ltf.ufpb.br (P.F.A.-F.) * Author to whom correspondence should be addressed; E-Mail: leoniab@.br; Tel.: +55-83 Fax: +55-83 Received: 29 January 2012; in revised form: 26 February 2012 / Accepted: 28 February 2012 / Published: 8 March 2012 Abstract: This review of the current literature aims to study correlations between the chemical structure and gastric anti-ulcer activity of tannins. Tannins are used in medicine primarily because of their astringent properties.