the giant cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of life巨人cafeteria roenbergensis病毒感染广泛的海洋吞噬原生生物是第四域的新成员的生活.pdfVIP
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the giant cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of life巨人cafeteria roenbergensis病毒感染广泛的海洋吞噬原生生物是第四域的新成员的生活
The Giant Cafeteria roenbergensis Virus That Infects a
Widespread Marine Phagocytic Protist Is a New Member
of the Fourth Domain of Life
1,2 1 ¨ 1 1 1,2
Philippe Colson , Gregory Gimenez , Mickael Boyer , Ghislain Fournous , Didier Raoult *
´ ´
1 Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Centre National de la Recherche Scientifique (CNRS) Unite Mixte de Recherche
´ ´ ´ ´ ´ ´ ˆ
(UMR) 6236 - Institut de Recherche pour le Developpement (IRD) 3R198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France, 2 Pole des
´ ´ ´ `
Maladies Infectieuses et Tropicales Clinique et Biologique, Federation de Bacteriologie-Hygiene-Virologie, Centre Hospitalo-Universitaire Timone, Marseille, France
Abstract
Background: A recent work has provided strong arguments in favor of a fourth domain of Life composed of nucleo-
cytoplasmic large DNA viruses (NCLDVs). This hypothesis was supported by phylogenetic and phyletic analyses based on a
common set of proteins conserved in Eukarya, Archaea, Bacteria, and viruses, and implicated in the functions of information
storage and processing. Recently, the genome of a new NCLDV, Cafeteria roenbergensis virus (CroV), was released. The
present work aimed to determine if CroV supports the fourth domain of Life hypothesis.
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