the human allergens of mesquite (prosopis juliflora)豆科灌木的人类过敏原(prosopis juliflora).pdfVIP

Clinical and Molecular Allergy BioMed Central Research Open Access The human allergens of mesquite (Prosopis juliflora) Sue Killian*1,2 and John McMichael1 Address: 1Dept. Research, The Institute for Therapeutic Discovery, P.O. Box 127, Delanson, New York, 12053, USA and 2The Institute for Therapeutic Discovery, 628 Kerns Mt . Ln., New Market, VA, 22844, USA Email: Sue Killian* - skillian@; John McMichael - titd@ * Corresponding author Published: 05 July 2004 Received: 23 April 2004 Accepted: 05 July 2004 Clinical and Molecular Allergy 2004, 2:8 doi:10.1186/1476-7961-2-8 This article is available from: /content/2/1/8 © 2004 Killian and McMichael; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permit- ted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: A computerized statistical analysis of allergy skin test results correlating patient reactivities initiated our interest in the cross-reactive allergens of mesquite tree pollen. In-vitro testing with mesquite-sensitized rabbits and a variety of deciduous tree pollens revealed so many cross-reactivities that it became apparent there could be more allergens in mesquite than previously described in the world literature. Our purpose was to examine the allergens of mesquite tree pollen (Prosopis juliflora) which elicit an IgE response in allergic humans so that fut