原创力文档cup blocks the precocious activation of the orb autoregulatory loop杯块orb的早熟的激活自动调整的循环.pdfVIP
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cup blocks the precocious activation of the orb autoregulatory loop杯块orb的早熟的激活自动调整的循环
Cup Blocks the Precocious Activation of the Orb
Autoregulatory Loop
¤
Li Chin Wong* , Paul Schedl
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
Abstract
Translational regulation of localized mRNAs is essential for patterning and axes determination in many organisms. In the
Drosophila ovary, the germline-specific Orb protein mediates the translational activation of a variety of mRNAs localized in
the oocyte. One of the Orb target mRNAs is orb itself, and this autoregulatory activity ens
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