谈头孢曲松钠致过敏性休克1例(Talking about 1 cases of anaphylactic shock caused by ceftriaxone sodium).docVIP
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谈头孢曲松钠致过敏性休克1例(Talking about 1 cases of anaphylactic shock caused by ceftriaxone sodium)
谈头孢曲松钠致过敏性休克1例(Talking about 1 cases of anaphylactic shock caused by ceftriaxone sodium)
Talking about 1 cases of anaphylactic shock caused by ceftriaxone sodium
Date: 2010, 01, 13
Ceftriaxone sodium is one of the most commonly used third generation cephalosporin antibiotics, and allergy is one of its side effects. Anaphylactic shock is the most serious allergic reaction, and the allergic constitution often occurs immediately after its application. This medicine and penicillin have partial cross allergy, so penicillin allergy history is used with caution, the person who is allergic to ceftriaxone sodium is forbidden. The patient had no history of penicillin allergy, negative for intradermal test of ceftriaxone sodium, and 3 consecutive d without allergy. Severe allergic shock occurred on the fourth day. It is rare in clinic. It may be associated with impure or low molecular weight impurities and their degradation products and proteins in the body to form allergic elements, which can induce allergic reactions of type 1. This situation deserves our colleagues to pay attention to.
Ceftriaxone sodium is widely used in clinic, and slight allergic reactions can be found in some allergic patients, such as rash, allergic dermatitis, urticaria, pruritus, erythema multiforme, bronchospasm, etc.. After anti allergy treatment, symptoms can disappear quickly. A very small number of severe allergic shock may occur, develop or die within seconds to minutes. I have seen a patient in the clinical use of continuous medication in the fourth day of severe allergic shock combined with stress gastrointestinal bleeding, after active rescue healed. The following abstracts are reported:
1 medical records
The patient, female, was 44 years old. Because of abdominal pain, chills, fever in 2 D patients. In 2 patients before D underwent excision of cervical polyp, postoperative lower abdominal pain occurred in the afternoon with fever chills, T Abstract: 37.8 DEG C, since the antibiotics at home
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