药理学复习重点简答(全)（Answer (full) review focus on Pharmacology）.docVIP

药理学复习重点简答(全)（Answer (full) review focus on Pharmacology） Two. Questions and answers 1. What medicine should organic phosphate be used to save? Answer: can use M receptor to block drug medicine: atropine, anisodamine, scopolamine and cholinesterase, resurrection drugs: chlorine solution phosphorus, iodine, phosphorus solution, double phosphorus and other rescue. 2, sulfa drugs and trimethoprim combination, can enhance the antibacterial effect 3, pilocarpine eye: miosis, reduce intraocular pressure and spasm of accommodation 4, antipyretic, analgesic and anti - drug action mechanism: inhibit prostaglandin synthetase activity and reduce prostaglandin biosynthesis in vivo. 5, the pharmacological action of hydrochlorothiazide: A, diuresis, the main role of the site in the distal convoluted tubule segment, inhibit the Na+-Cl- co translocation system, reduce the reabsorption of Na+ and Cl-, increase urine volume. Can also slightly inhibit carbonic anhydrase, so that K+ exclusion increased. B and hypotensive effect. C and antidiuretic effect. 6, adrenergic beta 2 receptor agonist, bronchial smooth muscle relaxation, relieve bronchial smooth muscle spasm; reduce bronchial submucosal capillary permeability, eliminate the bronchial mucosa hyperemia and edema, improve lung ventilation to treat asthma. 7, Kato Purys mechanism of action: A, inhibit angiotensin converting enzyme, B, and reduce the degradation of peptide. 8, epilepsy big attack first choice medicine: phenytoin sodium. Petits first choice: C Masi Bing 9, erythromycin antibacterial mechanism: with the bacterial ribosome 50S subunit binding, inhibit the peptidase, block peptide chain extension, thereby inhibiting bacterial protein synthesis. 10, the stability of the pharmacological and clinical use: pharmacological effects: anti anxiety, sedation, hypnosis, central muscle relaxation, etc.; clinical mainly used for anxiety disorders, insomnia, anti epileptic and anti shock que. 11, characteristics of quinolone drugs: A