药理笔记（Pharmacological notes）.docVIP

药理笔记（Pharmacological notes） 1 complimentary pharmacological notes summary First, the pharmacological effects (characteristics) and mechanisms of drugs 1. pilocarpine: M like action (antagonized by atropine). Myotic, intraocular pressure regulation and spasm of accommodation. Used of glaucoma. 2. neostigmine: cholinesterase inhibitors. For myasthenia gravis, postoperative abdominal flatulence and urinary retention, paroxysmal supraventricular tachycardia, detoxification of muscle relaxants. It is contraindicated in bronchial asthma, mechanical bowel obstruction, and urinary obstruction. M like action can be antagonized by atropine. 3. iodine phosphorus release: cholinesterase, a common remedy for organophosphate poisoning. Should be temporary configuration, intravenous injection. 4. atropine: M receptor blocker. Agonistic antagonism of Ach or cholinergic drugs to the activation of M cholinergic receptors. Used to relieve smooth muscle spasm, inhibit glandular secretion, iris, uveitis, fundus examination, optometry, anti infection, toxic shock, anti arrhythmic, rescue organophosphate poisoning. Disable in glaucoma and prostate hypertrophy patients disable. Sedative and anticonvulsant actions were used to counter the central excitatory symptoms of atropine, while atropine was administered with anticholinergic drugs, pilocarpine, or physostigmine. Scopolamine, a similar drug. Synthetic substitutes: mydriatic: homatropine. Propantheline antispasmodic. Acid suppressing drugs: prazosin, Xiping. Ulcerative drug: atropine methyl atropine. 5. scopolamine anisodamine function: scopolamine, central sedation and inhibition of glandular secretion, stronger than atropine. There are anti corona antiemetic effect, the treatment of Parkinsons disease. Anisodamine can improve microcirculation. It is mainly used for various infections, toxic shock, and also for the treatment of visceral smooth muscle angina, acute pancreatitis. 7. succinylcholine: quick acting short acting muscle relax