前列腺液白细胞计数及细菌培养关系.docVIP

前列腺液白细胞计数及细菌培养关系 　 作者：彭风华，杨金瑞，赵小昆，张选志，刘任，杨罗艳 【关键词】 前列腺炎 The relationship between bacterial culture and leukocyte count in expressed prostatic secretion 　　ABSTRACT: Objective To explore the relationship between bacterial culture and leukocyte count in expressed prostatic secretion. Methods EPS (expressed prostatic secretion) of 962 patients with prostatitis was examined, with leukocyte counted, during Sep. 2002 to Jan. 2005. 385 patients with leukocyte count gt;10/HP were classified as the research group; 577 patients with leukocyte count lt;10/HP were classified as the control group. At the same time, aerobic bacterial culture and Chlamydia culture as well as Mycoplasm culture were conducted. Results Of the 962 cases, 244(25.4%) cases of bacterial culture were positive. The total bacterial strains cultured were 285. With the leukocyte count stratified as +, , , in the research group, the positive rate of bacterial culture of EPS was 22.5%, 31.0%, 47.0% and 89.3% respectively. In the control group, the positive rate of bacterial culture of EPS was 19.6%(Plt;0.05). Conclusion With the increase of the leukocyte count, the positive rate of bacterial culture of EPS goes up gradually, which helps early prediction of bacterial culture results. 　　KEY WORDS: prostatitis; bacterial culture; leukocyte count 　　摘要：目的 探讨前列腺液白细胞计数与细菌培养的关系。方法 对2002年9月至2005年1月间，我院泌尿外科门诊962例前列腺炎患者行前列腺液常规检查，计数白细胞。白细胞数目gt;10个/高倍镜者为观察组共385例，白细胞数目lt;10个/高倍镜者为对照组共577例，同时行前列腺液需氧细菌培养以及支原体、衣原体培养。结果 962例前列腺液标本中，有244例(25.4%)病原体培养阳性，共计培养出病原体285株。研究组白细胞数目为+、、、时，细菌培养阳性率分别为19.6%、22.5%、31.0%、47.0%、89.3%，对照组前列腺液细菌培养阳性率为19.6%，两组间差别有显著性意义(Plt;0.05)。结论 随着前列腺液中白细胞数目的增加，细菌培养阳性率逐渐增高，有助于早期预测细菌培养结果。 　　关键词：前列腺炎；白细胞计数；细菌培养 　　细菌感染引起前列腺炎发病所占比例虽然不高，只有5%-10%，但却占据重要地位。四杯法细菌培养是诊断的金标准，但在临床工作中并非是最常采用的方法，尤其是对于基层医院而言，前列腺液常规检查依然是大部分医师的首选检查。前列腺液常规检查本身蕴含着相当丰富的疾病信息，前列腺液白细胞计数在初步判断有无细菌感染方面可以提供更多的帮助。本文试图通过深入分析前列腺液中白细胞数目与细菌培养的关系，在预估有无细菌感染方面作进一步探索。 　　1 对象与方法 　　1.1 研究对象 2002年9月-2005年1月泌尿外科门诊具有完整病史及诊疗记录和实验分析,符合美国国立卫生研究院(NIH)前列腺炎诊断标准的患者为研究对象。病例