the predictive value of eosinophil cationic protein and lactate dehydrogenase in asthma a comparative study of serum versus sputum嗜酸性粒细胞阳离子蛋白的预测价值和乳酸脱氢酶在哮喘血清与唾液的比较研究.pdfVIP
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the predictive value of eosinophil cationic protein and lactate dehydrogenase in asthma a comparative study of serum versus sputum嗜酸性粒细胞阳离子蛋白的预测价值和乳酸脱氢酶在哮喘血清与唾液的比较研究
ORIGINAL ARTICLE
The Predictive Value of Eosinophil Cationic Protein and
Lactate Dehydrogenase in Asthma: A Comparative Study of
Serum Versus Sputum
Amina Hamed Ahmad Al Obaidi, PhD, 1 Abdul Ghani Mohamed Al Samarai, MD, PhD, 1
Jasim Al-Janabi, PhD,2 and Abdulkareem Yahia, PhD3
(ECP) may be useful, indirect marker of airway inflammation
Background: Serum and sputum eosinophil cationic protein (ECP) 3 4
in asthma. Pizzichini et al reported that proportion of
levels are correlated with asthma disease severity.
eosinophils in sputum is a more accurate marker of asthmatic
Objective: To establish a diagnostic accuracy of ECP and lactate
airway inflammation than the proportion of blood eosinophils
dehydrogenase (LDH) in serum (indirectly) and sputum (directly) as 5
or serum ECP. Recently, Jang et al reported that the propor-
inflammatory markers in asthma.
tion of eosinophils in sputum have more accurate diagnostic
Patients and Methods: In a cross sectional study, 76 asthmatic
markers of asthmatic airway inflammation than NO metabo-
patients with exacerbation were enrolled in the study. ECP was
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