抗菌药物使用抽样调查探究.docVIP

抗菌药物使用抽样调查探究 　【摘要】 目的：分析临床抗菌药物使用过程中存在的问题，了解其中的不合理因素，进一步指导临床合理用药。方法：对2005年1月至2006年12月的住院患者按内、外、妇、儿科随机抽样1000例，对病情及抗菌药物使用情况进行分析。结果：手术病例抗菌药物使用率58.1%，在手术病例中使用率100%；非感染性疾病抗菌药使用率为2.3%，适应症比率为47.8%；疗程最长者33天；联合用药率75.9%；手术病例使用前三位用药为喹诺酮类（31.5%）、三代头孢（18.1%）、一代头孢（9.8%）；非手术病例使用前三位用药为三代头孢（20.7%）、大环内酯类（7.4%）、喹诺酮类（7.3%）。三代头孢及喹诺酮类抗菌药总使用率均为38.8%。结论：①手术病例抗菌药使用率高；②发热病人或无明确感染病例使用抗菌药；③抗菌药物使用疗程偏长；④部分抗菌药物用法不规范；⑤三代头孢及喹诺酮类抗菌药物使用率高；⑥抗菌药物联合用药率高。 【关键词】 抗菌药物； 使用；抽样；调查 　　The Sampling Investigation on Using Antibiotics 　　　(Chifeng Second Hospital, Neimenggu Chifeng 024000, China)Abstract： Objective： To analyze the problems and improper factors in using antibiotics , Try to have a guidance on using antibiotics. Method： From Jan. 2005 to Dec. 2006 , 1000 cases were selected to analyze the condition of patients and the use of antiotics. Result： In all cases , the using rate of surgical cases was 58.1% , in all surgical cases , the using rate was 2.3% , the ratio of indications was 47.8% . The longest therapeutic time was 33 days ; The rate of united using antiotics was 75.9% . In surgical cases, the using rates of three kinds of antiotics were on front : quinolones (31.5%). The third generation cephalosporins (18.1%); the first generation cephalosporins (9.8%) ; In non-surgical cases , the using rates of three kinds of antiolics were on front : the third generation cefhalosporins (20.7%) , macrolides (7.4%) , quinolones (7.3%) . the rates of quinolones and the third generation cephalosporins all were 38.8% . Conclusion： ①The using rates of surgical cases were high . ②Antiolics were used to the cases who had a fever or had infections diseases . ③The using time was a little long .④Parts of antiotics weren’t used standard. ⑤The using rate of quinolones and the third generation cephalosporins were high .⑥The united using rate of antiotics was high .Key words： Antiotics； Use； Sample； Investigation 　　抗菌药物的临床应用越来越广泛，在抗菌药挽救了许多患者生命的同时，也出现了由于抗菌药物不合理应用导致的不良后果，给患者造成极大影响。为更好指导临床合理使用抗菌药，现就我院2005年1月至2006年12月住院患者，随机抽