血清降钙素原的测定及临床意义（Determination of serum procalcitonin and its clinical significance）.docVIP

血清降钙素原的测定及临床意义（Determination of serum procalcitonin and its clinical significance） Determination of serum procalcitonin and its clinical significance Release time is 03 years, 04 months, 14, 12:48 Serum CT (Calcitonin) is the first peptide hormone extracted from the culture medium of thyroid tumor cells. Therefore, it is a serological marker of this tumor. PCT, the precursor of CT, 116 amino acid glycoprotein in the human body has a half-life of about 20-24 hours, the stability is good; in normal serum content is very low, in addition to thyroid trauma or tumor, systemic inflammatory response syndrome (SIRS) and serum of patients with sepsis, acute and chronic pneumonia, acute pancreatitis, activity hepatitis, trauma increased significantly, especially for SIRS/ PCT (sepsis, compared with WBC, IL-6, TNF-2, CRP, soluble P-selectin etc.) is a very sensitive and specific serological marker. In the factors of disease virus infection, trauma, tumor markers remain low, PCT in severe bacterial infection (2-3 hours) in early stage can be increased, so it has the value of early diagnosis; in local infection, virus infection, chronic non-specific inflammation, cancer fever, graft host rejection or autoimmune diseases when the PCT concentration increased or slightly increased, but in severe systemic infection was significantly increased, which determines the high specificity of PCT, so it can be used for differential diagnosis of various clinical conditions; the PCT concentration and the severity of inflammation was positively associated with inflammation and disease control and mitigation decreased to the normal level, so PCT can be used to evaluate the condition and prognosis and the curative effect of the reliability index. PCT has a wide and important clinical value, and provides standard for mortality and length of hospital stay in ICU patients. PCT can be widely used in ICU ward, Department of Hematology, oncology, pediatrics, premature and neonatal care room, surgery, i