血栓（thrombus）.docVIP

血栓（thrombus） In vivo cardiac or vascular cavity, blood coagulation or blood viscosity in the formation process of each visible component of a solid mass, known as thrombosis (thrombosis), the formation of a solid mass called thrombosis (thrombus). There is an antagonistic blood coagulation system and an anticoagulant system in the blood that maintain homeostasis in physiological conditions. However, sometimes, in the course of certain factors that promote the clotting process, breaking the dynamic balance triggers the clotting process, which can clot in the cardiovascular cavity and form clots. First, the conditions and mechanisms of thrombosis 1. cardiovascular intimal injury: cardiovascular endothelial cell is a single cell membrane that separates endothelial tissue and blood coagulation factors and platelets, and has the function of anticoagulation, antiplatelet and adhesion. However, when endothelial cells are damaged, the Willebrand factor may be synthesized, allowing platelets to adhere to the collagen under the endothelium. Because of endothelial injury, basement membrane collagen, fibril collagen and elastin are strongly procoagulant, leading to platelet adhesion and thrombosis. 2. changes in vascular status: when the blood flow slows, the blood flow stops and the vortex forms, the normal blood flow is destroyed. Normally, the axial flow of blood is composed of red blood cells and white blood cells. The outer layer is platelets, and the outermost peripheral stream is a layer of plasma that divides platelets from the intima. When the slow blood flow, stagnation into the vortex formation, platelet and endothelial cell contact opportunities, the endothelial cell degeneration and necrosis often occurs due to local hypoxia, blood coagulation factor, the thrombin concentration increased, can lead to thrombosis. Due to slow blood flow, and whirlpool, easy compression, more than arterial venous thrombosis, left atrial thrombosis in mitral stenosis, myocardial infarc