陈皮多甲氧基黄酮抗肿瘤作用及其机理地研究.pdfVIP

英文摘要 ．5． ABSTRACT Citrus fruitisthetraditionalChinesemedicine．Withthedefinitude oftheelementsin Citusfruit．theanticancereffectof the flavonesinCitrusfruit discoveredwhich polymethoxylated havebeen attractedattentioninrecent istheresearchabout great years．Thepaper the anticancereffectandthe mecanisim． pharmac0109ical PartI： researchofthedried s Pharmacodynamics tangerinepeel’ flavones． polymethoxylated 1 Effectsofthedried flavoneson tangerinepeel’spolymethoxylated tumorcell Dr01iferationinvitro Theanticancerofthedried activity tangerinepeel’spolymethoxy一 1atedflavoneswasobserved．Sixcancercell inthe strainswerechosen includedhumanlivercancercelllines experiment，which Be卜7402，human colonic cancercelllines cancercelllines HCT—116，humangastric bladdercancercell1ines cancercell BGC一823，human EJ，humanesophageal lines CaEs—17。andthemousesarcomaS180cell1ines．TheMTTmethodwas used，themicro—platereaderwasusedtodetecttheODvalueunderthe of630nm．Theresultshowsthatthedried s waVelength tangerinepeel’ flavonescan inhibitthesixcancercell polymethoxylated markedly 1ines．The anticancereffectbecome withthedosebecome s