重庆市九龙坡区2003-2011 年免费抗结核药利用效果分析.pdf

重庆市九龙坡区2003－2011年免费抗结核药利用效果分析 ＊ 詹跃强 ，吴燕燕（重庆市结核病防治所，重庆 400050） 中图分类号 R969.3；R287；R978.3 文献标志码 C 文章编号 1001-0408（2013）18-1647-03 DOI 10.6039/j.issn. 1001-0408.2013.18.06 摘 要 目的：评价重庆市九龙坡区免费抗结核药的利用效果。方法：收集重庆市九龙坡区2003－2011年肺结核初诊登记本、肺 结核患者治疗情况登记本、实验室痰涂片登记本、患者病历、年度工作报表等，对肺结核患者的治愈率、不良反应、治疗失败、死亡、 丢失、外迁情况等进行统计、分析。结果：利用政府提供的免费抗结核药（异烟肼、利福平、乙胺丁醇、吡嗪酰胺），共为4713例肺结 核患者进行治疗，治愈或完成疗程者有4318例，占治疗总数的91.62％。其中，初治涂阳1799例，治愈率为94.94％；复治涂阳173 例，治愈率为86.13％。结论：重庆市九龙坡区实施免费抗结核药治疗9年间效果显著，达到了世界银行贷款/英国赠款中国结核病 控制项目的要求，有效地控制了结核病在该区的蔓延。 关键词 肺结核；免费；抗结核药；治疗效果；不良反应；涂阳患者 Effect Analysis of Free Anti-TB Agents in Chongqing Jiulongpo District from 2003to 2011 ZHAN Yue-qiang ，WU Yan-yan （Chongqing Institute for TB Prevention and Treatment ，Chongqing 400050，China ） ABSTRACT OBJECTIVE ：To evaluate the effect of free anti-TB agents in Chongqing Jiulongpo district. METHODS ：First visit- ing records ，treatment records ，sputum smear records ，medical record of patients and annual report forms of pulmonary tuberculo- sis patients were collected in Chongqing Jiulongpo district from 2003－2011. Cure rate ，ADR ，treatment failure ，death ，missing ， outward migration ，in pulmonary tuberculosis patients were analyzed statistically. RESULTS ：Through treatment of free anti-TB agents （isonicotinyl hydrazide ，rifampicin ，ethambutol ，pyrazinamide ）by local government ，totally 4 713 pulmonary tuberculosis patients received treatment and 4 318patients were cured or received complete treatment course with ratio of 91.62％. There were 1 799cases of initial cure active tuberculosis with cure rate of 94.94％，173cases of retreatment with cure rate of 86.13％. CONCLU- SIONS ：In 9 years ，the practice of free anti-TB agents funded by Chongqing Jiulong district is effective ，which is in line with the requirements of WB/DFID TB control project and control the spreading of TB in the area effectively. KEY WORDS Pulmonary tub