黄酮类化合物的生物转化研究进展-广东农业科学.pdfVIP

广东农业科学 2013 年第4 期 95 黄酮类化合物的生物转化研究进展 1,2 1 1 赖剑峰 杨荣玲 刘学铭 (1.广东省农科院蚕业与农产品加工研究所/广东省农产品加工重点实验室/省部共建国家重点实验室培育基 袁 广东广州 510610 曰 2.江西农业大学生物科学与工程学院袁江西 南昌 330000冤 摘要 黄酮类化合物具有抗氧化尧抗肿瘤尧抗癌等生理活性袁但该类化合物存在脂溶性或水溶性较差尧生物利用率低尧稳定性 不好等缺点遥利用生物转化方法对其进行结构修饰袁可改善其溶解性袁增强其生理活性及稳定性遥对近年来黄酮类化合物生物转化 中的水解尧酯化尧糖基化等几种重要的生物催化反应进行了综述袁并对发展前景进行了展望遥 关键词 黄酮类化合物曰生物转化曰生物催化 中图分类号 Q586 文献标识码 A 文章编号 1004-874X 2013冤04-0095-04 Advances on biotransformation of flavonoid compounds 1,2 1 1 LAI J ian-feng , YANG Rong-ling , LIU Xue-ming (1. The Sericulture Farm Produce Processing Researc h Institute, Guangdong A cademy of A gricultural Sciences/G uangdong Key Lab of A gric ultural Product Process ing /Cultivation Base of State Key Laboratory Constructed by G uangdong Prov ince and Ministry of Science and Tec hnolgy, Guangzhou 510610, China; 2. College of Bioscience and Biotechnolgy, Jiangxi A gric ultural Unive rsity, Nanchang 330000, China ) Abstract: Flavonoids have antioxidant, anti-tumor, anti-cancer and other physical activity, but these compounds have some shortcomings of poor fat-soluble or water-soluble, low bioavailability and stability. Biotransformation of structural modification can improve solubility, and enhance physical activity and stability. This article reviewed several important bio-catalytic reactions in the biotransformation of flavonoids in recent years, hydrolysis, esterification, glycosylation, and prospect of biotransformation was anticipated. K