肉眼下行翼状胬肉逆行切除联合带角膜缘干细胞结膜瓣移植术疗效观察.docVIP

肉眼下行翼状胬肉逆行切除联合带角膜缘干细胞结膜瓣移植术疗效观察 　　[摘要] 目的 探讨肉眼下行翼状胬肉逆行切除联合带角膜缘干细胞的结膜瓣移植术的临床疗效。 方法 本院门诊对58例（65眼）原发性翼状胬肉患者，在肉眼下行翼状胬肉逆行切除联合带角膜缘干细胞的游离结膜瓣移植术，术后观察角膜创面愈合时间，眼部刺激症状程度及复发情况。 结果 术后第2天角膜创面光滑，刺激症状轻，随访6个月～2年，痊愈54眼，好转6眼，复发5眼，复发率为7.69%。 结论 肉眼下行翼状胬肉逆行切除联合带角膜缘干细胞的结膜瓣移植术，设备要求低，操作简单，费用低廉，术后刺激症状轻，复发率低，适合基层医院开展。 [关键词] 翼状胬肉；角膜缘干细胞；移植；复发 [中图分类号] R777.33 [文献标识码] A [文章编号] 1674-4721（2013）07（a）-0024-03 Clinical observation of primary pterygium excision combined with limbal stem cells transplantation and conjunctival autograft under direct vision DU Hong1 GUO Xiao-lan1 HUANG Zheng-mao2 TANG Zhi-ying1 DENG Wei-guang1 1.Department of Ophtalmology， Yangang Hospital in Shenzhen City of Guangdong Province， Shenzhen 518083， China；2.Department of Ophtalmology， Meisha Hospital in Shenzhen City of Guangdong Province， Shenzhen 518083， China [Abstract] Objective To observe the clinical effect of primary pterygium excision combined with limbal stem cells transplantation and conjunctival autograft under direct vision. Methods 58 cases of patients （65 eyes） with primary pterygium were given pterygium excision combined with limbal stem cells transplantation and conjunctival autograft under direct vision. Cornea healing time， stimulating symptoms and recurrent rate were observed. Results 1 day after operation， cornea surface were smooth， stimulating symptoms were light. All patients were followed up for 6-24 months， 54 eyes recovered， 6 eyes improved， 5 eyes reappeared， the recurrence rate was 7.69%. Conclusion Pterygium excision combined with limbal stem cells transplantation and conjunctival autograft under direct vision， which need simple equipment and lower cost， seems to be suitable for primary hospital. [Key words] Pterygium； Limbal stem cell； Transplantation； Recurrence 翼状胬肉是眼科常见眼表疾病之一，一般认为与紫外线刺激有关，常见于户外工作者，以农民、渔民多发，目前临床上治疗仍以手术为主[1-3]。显微镜下手术费用较高，本院2009年3月～2012年8月对明确诊断为原发性翼状胬肉的患者58例（65只眼），在门诊直视下行翼状胬肉逆行切除联合带角膜缘干细胞的结膜瓣移植术，术中注意仔细操作，术后加强随访及抗炎治疗，取得良好效果。 1 资料与方法 1.1 一般资料