卡前列素氨丁三醇与米索前列醇防治高危孕妇剖宫产术后产后出血的临床观察.pdfVIP

用药物与临床2014年第17卷第2期 PracticalPharmacyAndClinicalRemedies．2014．Vo1．17．No．2 卡前列素氨丁三醇与米索前列醇防治高危孕妇剖宫 产术后产后出血的临床观察 包智慧 ，龚晓华。 [摘 要] 目的 比较卡前列素氨丁三醇与米索前列醇对高危产妇剖宫产术产后出血的防治价值。方法 将 102例行剖 宫产分娩 的高危产妇随机分为 2组 。A组 52例 ，给 予卡前 列素氨 丁三醇肌注 ；B组 5O例 ，给予米 索前列醇塞肛治疗。比较两组产后 出血率、产后 2h及 24h出血量。结果 两组产后 出血率 比较差异无统计学 意义 (P0．05)；A组产后 2h及 24h出血 量均少于 B组 (P0．05)；两组 不 良反应发 生率 比较 差异无统计 学意 义 (P0．05)。结论 卡前列素氨丁三醇对产后 出血 的防治效果优于米索前列醇，可提高子宫收缩率，减少产后 出血率 。 [关键词] 产后 出血；剖宫产术 ；卡前列素氨丁三醇；米索前列醇；防治 Clinicalanalysisofcarboprosttromethamineand misoprostolin theprevention of postpartum hemorrhageofhigh-risk pregnantwomenaRercesarean section BAO Zhih·ui，GONGXiao—hua(1．DepartmentofGynecologyandObstetrics，ChineseMedicineHospitalof-TmshunCoun— ty，Zhejiang325500，China；2．DepartmentofObstetricsandGynecology，ThePeoplesHospitalofTaishunCounty， Zhejinag3255o0，China) [Abstract] Objective Tocomparethevalueofcraboprosttromethamineandmisoprostolinhtepreventionand treatmentofpostl；)artum hemorrhagein high—risk pregnna twomen aftercesarena section．M ethods 102 casesofhigh— risk pregnna twomen were rna domly divided into 2 groups，52 cases in group A were treated with carboprost tromethamine，while52 cases in group B were treated wiht misoprosto1．Thepostpattani hemorrhage rate and hte amountofbleedingwerecompraedbetweenthetWOgroups．Results Therewasno significna tdifferencein thepost— partum hemorrhageratebetweenhte2groups(尸0．05)．Thema ountofbleedingatpostpartum 2hnad24hingroup A werelesshtna htoseofgroupB(P0．05)．Nosignificnatdifferencewasfoundintheincidenceofadversereactions betweenhte2groups(P0．05)．Conclusion Craboprostrtomethaminecanpreventpost[Iartum hemorrhage，nadthe effectissuperiortO thatofmisoprostol，itcanimprovetherateofconrtactionofhteuterus，na dreducehterateofpost— partum hemorrhage． Keywords：Post[)artum hemorrhage；Cesareansection；Carbopros