盐酸利托君用于治疗前置胎盘疗效观察.docVIP

盐酸利托君用于治疗前置胎盘疗效观察 　　[摘要] 目的 探讨盐酸利托君用于治疗前置胎盘的临床疗效。 方法 将100例患者随机分为观察组和对照组各50例，观察组给予盐酸利托君治疗，对照组给予硫酸镁治疗。 结果 观察组患者24 h出血停止率、保胎成功率、延长孕周、妊娠期≥36周比率及新生儿1 min Apgar评分均优于对照组（P0.05），两组均有不同的药物不良反应，两组不良反应发生率比较差异无统计学意义（P0.05）。 结论 应用盐酸利托君治疗前置胎盘疗效显著，能够有效抑制宫缩，保胎成功率高，具有起效快、控制出血效果好、作用强等优点，值得临床推广。 [关键词] 前置胎盘；盐酸利托君；硫酸镁 [中图分类号] R714.21 [文献标识码] B [文章编号] 2095-0616（2013）13-65-02 Observation of the clinical curative effect of ritodrine hydrochloride on placenta previa LIN Shaomin The First People’s Hospital of Dongshan District Pandong Town，Jieyang City， Guangdong Province，Jieyang 522071，China [Abstract] Objective To investigate the clinical curative effect of ritodrine hydrochloride on placenta previa. Methods 100 patients were randomLy divided into observation group and control group （50 cases in each group）.The observation group was treated with ritodrine hydrochloride and the control group was treated with magnesium sulfate. Results The cessation rate of hemorrhage in 24 h，success rate of tocolysis，increased gestation age，the ratio of ≥36 week gestation and 1 min Apgar score of newborns of the observation group were superior to the control group （P0.05）.Different adverse drug reactions were found in both groups with no statistical significance of the incidence（P0.05）. Conclusion The application of ritodrine hydrochloride placenta previa has obvious therapeutic effect，which can effectively inhibit the uterine contraction with high success rate of tocolysis and advantages of rapid onset and good control effect on hemorrhage，which is worthy of clinical promotion. [Key words] Placenta previa；Ritodrine hydrochloride；Magnesium sulfate 前置胎盘是指正常妊娠胎盘附着处于子宫体部的前后壁或侧壁，妊娠28周后若胎盘附着处于子宫下段甚至胎盘下缘达到或覆盖宫颈内口，位置较之胎儿先露部低的情况，是妊娠晚期的严重并发症，亦是妊娠晚期出血的主要原因之一[1]。妊娠晚期无诱因、无痛性的反复阴道流血是前置胎盘的主要表现，若处理不当，将会危及母婴的生命安全。在对前置胎盘的治疗中，有文献表明治疗成功的关键是抑制宫缩、延长孕龄及减少产前出血[2]。2007年6月～2011年6月，我院应用盐酸利托君对50例前置胎盘患者进行治疗，取得了较好疗效，现报道如下。 1 资料与方法 1.1 一般资料 选取2007年6月～2011年6月我院收治的100例前置胎盘患者，均符合《妇产科学》[3]中前置胎盘的诊断标准，并经B超检查确