两种不同子宫动脉灌注化疗方案结合栓塞术的疗效及安全性评价.docVIP

精品论文 参考文献 两种不同子宫动脉灌注化疗方案结合栓塞术的疗效及安全性评价 1陕西省榆林市靖边县妇幼保健院 妇产科 ，陕西榆林，718500 2陕西省榆林市榆阳区疾病预防控制中心 妇产科，陕西榆林，719000 作者简介： 第一作者：张卉玲（1984.12-），女，学历：本科；职称：主治医师；主要研究方向：妇科肿瘤 Two different uterine arterial embolization combined with chemotherapy efficacy And safety evaluation 【摘要】：目的：研究两种不同子宫动脉灌注化疗方案结合栓塞术对异位妊娠的临床治疗效果及安全性作用。方法：随机从我院接诊的异位妊娠患者中抽取80例均分为两组进行治疗，即对照组和观察组 [1]。对照组采用单纯的甲氨蝶呤灌注治疗，观察组采用甲氨蝶呤外加5-氟尿嘧啶灌注结合栓塞术的治疗方法。观察两组患者术后的恢复时间、血beta;-HCG值、输卵管畅通率等，并观察不良反应发生情况，分析两组统计数值差异。结果：经过临床干预后，两组患者的症状均有好转，而对照组患者的发生不良事件概率较低，与观察组相比，安全性更高（Plt;0.05）。对照组的平均治疗时间为（26.73plusmn;5.56）d，治疗组为（28.52plusmn;5.07)d，Pgt;0.05。对照组和观察组的输卵管通畅率分别为80.0%、75.0%，两组差异不明显，Pgt;0.05。结论：通过两种治疗方法的临床实验效果比较，对照组患者的不良反应人数少于于观察组。单纯的甲氨蝶呤灌注方法治疗异位妊娠疾病更有效。 Abstract: Objective: To study two different uterine artery infusion chemotherapy combined with ectopic pregnancy clinical efficacy and safety of the role of embolization. Methods: 80 cases were randomly selected from patients with ectopic pregnancy in hospital admissions for treatment were divided into two groups, namely the control group and the observation group [1]. The control group was simply methotrexate infusion treatment, observation group were combined with methotrexate plus 5-fluorouracil infusion therapy embolization. Postoperative recovery time for both groups of patients, serum beta;-HCG value, tubal patency rates of other adverse events were observed, the statistical analysis of two numerical differences. Results: After a clinical intervention, both groups of patients had improvement in symptoms, while a lower probability of adverse events occurred in patients in the control group compared with the observation group, more secure (P lt;0.05). The average treatment time for the control group (26.73 plusmn; 5.56) d, the treatment group (28.52 plusmn; 5.07) d, Pgt; 0.05. The control group and the observation group tubal patency rate was 80.0 percent, respectively, 75.0%, no significant difference between the two groups, Pgt; 0.05. Conclusion: The clinical trial comparin