妊娠期糖尿病且产后IGT患者强化生活方式干预后糖代谢和体重控制情况观察.docVIP

精品论文 参考文献 妊娠期糖尿病且产后IGT患者强化生活方式干预后糖代谢和体重控制情况观察 1南华大学附属南华医院内分泌科，湖南衡阳，421002 2南方医科大学珠江医院内分泌科，广东广州，510282 项目资助：2014年湖南省卫生厅课题，项目编号C2014-66 Delta; 通讯作者，李国娟，博士研究生，Email：524008651@ [摘要]目的 研究妊娠期糖尿病且产后糖耐量减低（IGT）患者采用强化生活方式干预后糖代谢和体重控制情况。方法 选择2013年1月至2014年1月有妊娠期糖尿病并在产后第6-8周诊断为糖耐量减低（IGT）的60例产妇进行研究。用随机数字表法随机分为干预组和对照组各30例，干预组进行强化生活方式干预，而对照组仅按诊疗常规进行处理。对比产后12个月时两组患者的糖代谢及体重控制情况和满意率。结果 产后12个月时，强化生活方式干预组较对照组的OGTT空腹血糖及服糖后2小时血糖、HbA1c、体重均低于对照组，差异有统计学意义（Plt;0.05）；干预组满意率更高，干预组满意率为93.3%，对照组满意率为80.0%，差异有显著统计学意义（Plt;0.01）。 结论 强化生活方式干预能有效改善妊娠期糖尿病且产后IGT患者的糖代谢和体重控制情况。 【关键词】生活方式干预；妊娠期糖尿病；IGT The effect of intensive lifestyle intervention on glucose metabolism and weight control in Gestational diabetes mellitus and postpartum IGT patients Li Guojuan1,2, Guo Hui1, Li Jing1, Xiao Zhifang1 1Department of Endocrinology, First Affiliated Hospital, University of South China, Hengyang 421001, China 2Department of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China Corresponding author：Li Guojuan, Email:524008651@ [Abstract] Objective: To study the effect of glucose metabolism and weight control in Gestational diabetes mellitus and postpartum impaired glucose tolerance( IGT) patients treated by intensive lifestyle intervention. Methods: Selected 60 patients with gestational diabetes mellitus and postpartum impaired glucose tolerance( IGT) during January 2013 to January 2014. According to the random number table, the patients were randomly divided into intervention group and control group. Each group had 30 cases. The patients in the intervention group were given intensive lifestyle intervention, whereas the patients in the control group were only given routine clinical intervention. Glucose level, weight and the degree of satisfaction were compared in two groups after postpartum 12 months. Results: Fasting plasma glucose, 2 hours plasma glucose after taking sugar in OGTT, HbA1c and weight of patients in intervention group were lower than those of patients in contro