妊娠期糖尿病对婴儿血脂代谢影响及相关因素分析.docVIP

精品论文 参考文献 妊娠期糖尿病对婴儿血脂代谢影响及相关因素分析 董旭 姜红 　　（青岛大学附属医院新生儿科 山东 青岛 266000） 　　【摘要】目的：探讨糖尿病母亲糖代谢紊乱对新生儿血脂代谢的影响。方法：将2007-2014年间入住青岛大学附属医院的88例糖尿病母亲婴儿的相关资料进行收集和回顾性分析，并选择同一时期入住本院的108例非糖尿病母亲婴儿作为对照组，比较两组间的血脂水平有无显著性差异，并分析糖尿病母亲婴儿的血脂水平与婴儿性别、血糖、胎龄及出生体重之间的关系。结果与结论：糖尿病母亲婴儿血总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白及脂蛋白a的水平均较非糖尿病组高。糖尿病母亲婴儿女性与男性相比，血总胆固醇、高密度脂蛋白及低密度脂蛋白水平均高于男性。随着糖尿病母亲婴儿胎龄和出生体重的增加，血总胆固醇和高密度脂蛋白水平增加。 　　【关键词】糖尿病母亲婴儿；血总胆固醇；甘油三酯；高密度脂蛋白；低密度脂蛋白；脂蛋白a 　　【中图分类号】R714.25 【文献标识码】A 【文章编号】2095-1752（2015）10-0044-02 　　 Analysis of serum lipid levels in infants born of diabetic mothers 　　Dong Xu,Jiang Hong The Affiliated Hospital of Qingdao University, Shandong Province, Qingdao 266000, China 　　【Abstract】 Objective By comparing serum lipid levers in infants of diabetic mothers and non-diabetic mothers, we try to find difference between them. Methods The data of 88 cases of infants of diabetic mothers were collected during 2007-2014 from the affiliated hospital of Qingdao university and analyzed retrospectively. The serum lipid levels in infants of diabetic mothers and non-diabetic mothers were compared, the collection between serum lipid levels, sex, fetal age, blood glucose and birth weight was analyzed. Results and Conclusion The serum lipid levels in infants of diabetic mothers were higher than those of non-diabetic group. Among the infants born of diabetic mothers, the serum levels of cholesterol, high density lipoprotein and low density lipoprotein in female infants were higher than male infants. Cholesterol and high density lipoprotein were higher as age and birth weight grower. 　　【Key words】Infants of diabetic mothers; Cholesterol; Triglyceride; High density lipoprotein; Low density lipoprotein; Lipoprotein a 　　随着人们生活水平的日益提高，妊娠期糖尿病发病率逐年增加，糖尿病母亲婴儿是临床上常见的一类高危儿。因孕母体内糖代谢紊乱导致新生儿出生后发生低血糖、呼吸窘迫综合征、先天性心肌肥厚、先天性畸形的发病率大大提高[1]。有研究发现[2，3]，糖尿病母亲婴儿的脂蛋白代谢存在异常，这可能是糖尿病母亲婴儿将来发生冠心病和动脉粥样硬化的重要原因。因此，本文通过对2007-2014年间青岛大学附属医院收治的88例糖尿病母亲婴儿的临床资料进行整理和回顾性分析，深入了解妊娠期糖尿病对婴儿血脂代谢的影响。 　　1.资料与方法