屈光不正性弱视儿童治疗前后图形视觉诱发电位的临床分析.docVIP

屈光不正性弱视儿童治疗前后图形视觉诱发电位的临床分析 张学印　徐西玲 　　威海市立第二医院眼科　山东　威海　２６４２００ 　　【摘要】　目的　对屈光不正性弱视儿童治疗前后图形视觉诱发电位(PVEP)的临床治疗结果进行探析.方法　以我院２０１２年１月至２０１４年１２月收治的８６例１７２眼屈光不正性弱视儿童患儿为研究对象,作为观察组,同时期选取４４例健康儿童作为对照组,以进行对比分析,观察与比较两组以及观察组内不同弱视程度的患儿的PVEP的p１００振幅(AP１００)与P１００潜伏期(LP１００),并观察不同弱视程度的患儿的治疗效果.结果　两组患儿PVEP的AP１００与LP１００均存在显著差异性(P＜０．０５).轻度弱视患儿的治疗有效率与基本治愈率分别是１００％、８６．４％,中度患儿分别是１００％、６９．０％,重度患儿分别是９２％、５１．７％,差异性显著(P＜０．０５).重度弱视患儿的潜伏期最长,且治疗效果最差,与中度患儿、轻度患儿存在显著差异性(P＜０．０５).结论　通过对弱视儿童治疗前及治疗后进行图形视觉诱发电位的测定,可以反应视功能损坏的程度,对视功能恢复情况的评价具有一定的价值. 【关键词】　弱视,儿童;　图形视觉诱发电位;　潜伏期;　振幅ClinicalAnalysisonRefractiveAmblyopiaBasedonGraphicVisualEvokedPotentialChangesbeforeandafterTreatmentonChildren　ZhangXueyinXuXiling 　 (DepartmentofOphthalmology,WeihaiMunicipalSecond Hospital,Weihai,Shandong,２６４２００)【Abstract】　objective:ToanalyseclinicaltreatmentresultsofrefractiveamblyopiabasedonPatternvisualevokedpotentialchangesbeforeandaftertreatＧmentonchildren．Methods:Contrastiveanalysiswascarriedoutinobservationgroup(８６casesofchildrenwithamblyopiachildrenreceivedinourhospitalfromJ(anuary２０１２toDecember２０１４astheresearchobject)andcontrolgroup(４４casesofhealthychildren )tofindoutamplitudeofp１００ (AP１００)orlatency LP１００)andthetherapeuticeffectofdifferentdegreeofamblyopiachildren．Results:Thereexistssignificantdifference(P ＜０．０５)betweentwogroupsofsickchildrenbothinAP１００andLP１００．Childrenwithmildamblyopiatreatmentefficientandbasiccureratewere１００％,８６．４％;moderatechildrenwere１００％,６９．０％,andseverepatientswere９２％,５１．７％．Thelatencyofsevereamblyopiachildrenwasthelongestandthetreatmenteffectwastheworst,whichwasgreatlydifferentfrom moderateandmildsickchildren．Conclusion:DamagedegreesofvisualfunctioncanbereflectedthroughdetectingpotentialchangesevokedbypatＧternv【iKseuyalwboerfdosre】andaftertreatmentonchildren,whichisvaluableintheevaluationonvisualfunctionalrecovery． 　Amblyopia;　Children;　Patternvisualevokedpotentials;　Latency;　Amplitude 【中图分类号】R７７７　　【文献标识码】B 　　【文章编号】１００１－５３０２(２０１５)０９－０７６０－０２　　 　　视觉[１]属于发育性的一种感知功能,弱视属于儿童群体在发育阶段的一种多发的眼病,在儿童眼病患病总数中占２—３％[２],一旦发现与诊治不及时,