慢性充血性心力衰竭的临床疗效观察.docVIP

精品论文 参考文献 慢性充血性心力衰竭的临床疗效观察 武汉市黄陂区中医院内科 湖北武汉 430300 【摘 要】目的：探讨美托洛尔联合西拉普利治疗慢性充血性心力衰竭（CHF）患者的临床疗效。方法：将CHF患者86例随机分为观察组和对照组，每组各43例，对照组给予常规利尿剂、地高辛、硝酸盐、螺内酯等抗心力衰竭药物进行治疗，观察组在对照组基础上，加用美托洛尔联合西拉普利治疗，两组患者6个月为1个疗程。并观察患者心功能分级、左室舒张末期内径、收缩末期内径、左室射血分数。结果：观察组总有效率为97.67%（42/43），对照组则为79.07%（34/43），两组比较差异有统计学意义（Plt;0.05）。结论：在强心利尿的基础上，美托洛尔联合西拉普利治疗CHF可明显改善患者左心室功能等临床症状，其临床治疗效果显著。 【关键词】慢性充血性心力衰竭；美托洛尔；西拉普利 The clinical effect of the treatment of chronic congestive heart failure Li yong （huangpi district in wuhan city of traditional Chinese medicine Hubei wuhan 430300） [abstract] objective：to study the metoprolol combined Silas captopril in patients with chronic congestive heart failure（CHF）in patients with clinical efficacy.Methods：86 patients with CHF were randomly divided into observation group and control group，each group 43 cases，control group given conventional diuretic，digoxin，nitrate，spironolactone and other drug for heart failure treatment，observation group on the basis of control group，and treated with metoprolol combined Silas split，two groups of patients 6 months for a course of treatment.And observed in patients with cardiac function classification，left ventricular end-diastolic diameter，inner diameter and left ventricular end systolic ejection fraction.Results：observation group total effective rate was 97.67%（42/43），the control group was 79.07%（34/43），is similar between the two groups was statistically significant（P lt; 0.05）.Conclusion：on the basis of the strong heart diuresis，metoprolol combined Silas captopril treatment of left ventricular function in patients with CHF can significantly improve the clinical symptoms，such as the clinical treatment effect is remarkable. [key words] chronic congestive heart failure；Metoprolol；Silas split 慢性充血性心力衰竭（CHF）是由于多种不同疾病因素引起的心脏收缩和舒张功能受损，其中以心脏排血量缺乏，组织的血液灌注减少以及肺循环或体循环静脉系统淤血为特征，它是一种临床综合征，预后差、病死率高[1]。CHF是严重影响人类健康的重要疾病之一，伴随着我国经济的高速发展，高血压、冠心病等疾病的发病率逐渐增加，心脏疾病终末阶段的CHF患者人数急剧增多。而随着心力衰竭（HF）产重程度的增加，致使CHF加重而导致死亡的患者也在不断增多。CHF患者总体预后极差，因此，