探讨他汀类药物在冠心病治疗中的应用.docVIP

精品论文 参考文献 探讨他汀类药物在冠心病治疗中的应用 绥化市北林区西长发镇中心卫生院 152000 　　摘要：目的：研究分析他汀类药物在冠心病治疗中的作用。方法：此次研究的对象是选择2010年1月-2012年12月收治冠心病患者96例，将其临床资料进行回顾性分析，并随机分为常规治疗组和他汀类药物治疗组，各48例。对两组患者治疗前后的血脂水平及心血管不良事件的发生率进行统计分析。结果：两组患者的血脂在治疗后均较治疗前下降，但他汀药物治疗组血脂下降程度明显高于常规治疗组，差异有统计学意义。他汀类药物治疗组的心血管不良事件的发生率也明显低于常规治疗组，并且他汀类药物的不良反应较小。结论：对冠心病患者进行他汀类药物调脂治疗，可以有效稳定冠脉粥样斑块，减少心血管不良事件的发生率，改善患者的生存质量。 　　关键词：他汀类药物；冠心病治疗；应用效果 　　[Abstract] Objective：To study the effect of statins in the treatment of coronary heart disease.Methods：the subjects of this study is to select from December January 2010 -2012 year in patients with coronary heart disease in 96 cases，the clinical data were retrospectively analyzed，and randomly divided into routine treatment group and the statin treatment group，48 cases in each.The lipid levels of two groups of patients before and after treatment and the incidence of cardiovascular adverse events were statistically analyzed.Results：the blood lipid of the two groups were decreased after treatment than before treatment，but the level of serum lipids in the statin treatment group was significantly higher than that in the conventional treatment group，the difference was statistically significant.The incidence of adverse cardiovascular events in statin therapy group was significantly lower than that in the conventional treatment group，and the adverse reactions of statins were smaller.Conclusion：statin therapy for coronary heart disease patients can effectively stabilize the plaque，reduce the incidence of adverse cardiovascular events，and improve the quality of life of patients with coronary heart disease. 　　[Key words] the effect of statin therapy on coronary heart disease 　　 　　 　　冠心病的危险因素之一就是高脂血症，控制血脂成为了预防及治疗冠心病的重要手段，目前调脂的药物主要是他汀类药物。本文通过分析研究辛伐他汀在治疗冠心病中的疗效，来总结他汀类药物在冠心病治疗中应用效果，现报告如下。 　　1资料与方法 　　1.1一般资料 　　2010年1月-2012年12月收治冠心病患者96例，随机分为两组，其中常规治疗组48例，男34例，女14例，年龄42～78岁，平均（56plusmn;4.5）岁，伴有高血压24例，糖尿病10例，高脂血症46例。 他汀类药物治疗组48例，男31例，女17例，年龄43～81岁，平均（54plusmn;5.8）岁，伴有高血压26例，糖尿病9例，高脂血症44例。两组在年龄、性别、疾病分类、疾病程度上差异无统计学