探讨纳洛酮对急性脑外伤出血患者的临床疗效.docVIP

精品论文 参考文献 探讨纳洛酮对急性脑外伤出血患者的临床疗效 鸡西市精神病防治院 158100 摘要：目的：此次研究的纳洛酮对急性脑外伤出血患者的临床疗效。方法：此次研究的对象是选取笔者所在医院2011年4月-2015年2月收治的82例急性脑出血患者，将其临床资料进行回顾性分析，并按照入院的先后顺序将其分为观察组和对照组，每组41例。对照组患者采用常规治疗方法，观察组患者在此基础上增加纳洛酮进行治疗，对比两组患者的临床治疗效果。结果：两组患者经治疗后，观察组患者的临床治疗总有效率为95.12%，对照组为78.05%，两组比较差异有统计学意义（Plt;0.05）；两组患者治疗前的颅内压以及GCS比较差异均无统计学意义（Pgt;0.05），治疗后观察组患者的颅内压以及GCS均好于对照组，对照组心电图异常以及呼吸异常患者的例数均明显多于观察组，两组比较差异均有统计学意义（Plt;0.05）。结论：对急性脑外伤患者采用纳洛酮治疗，其治疗效果较为显著，此药具有一定的安全可靠性，值得在临床中推广应用。 关键词：纳洛酮；急性脑外伤；临床治疗效果 [Abstract] Objective：To study the clinical effect of naloxone in patients with acute cerebral hemorrhage. Methods：the research object is selected in the hospital in 2011 April 2015 February were 82 cases of acute cerebral hemorrhage patients，the clinical data were retrospectively analyzed，and in accordance with the admission of the sequence will be divided into the observation group and the control group，41 cases in each group. Patients in the control group were treated with routine treatment，the observation group was treated with naloxone on this basis，and the clinical treatment effect of the two groups were compared. Results：patients in the two groups after the treatment to observe the clinical treatment of patients，the total effective rate was 95.12%. 78.05% in the control group，the difference between the two groups has statistical significance（P lt; 0.05）；two groups of patients before treatment of intracranial pressure（ICP）and GCS，the difference had no statistical significance（P gt; 0.05），observation group of patients with intracranial pressure and GCS treatment were better than that of the control group，control group of abnormal ECG and respiration in patients with abnormal cases were significantly higher than those of the observation group，the two groups differences were statistically significant（P lt; 0.05）. Conclusion：the treatment of acute brain injury patients with naloxone，the treatment effect is more obvious，this medicine has certain safety reliability，it is worth in clinical application.