浅析免疫球蛋白治疗难治性免疫性血小板减少临床观察唐晓红.docVIP

精品论文 参考文献 浅析免疫球蛋白治疗难治性免疫性血小板减少临床观察唐晓红 大庆油田总医院 163000 【摘 要】目的：研究分析免疫球蛋白治疗难治性免疫性血小板减少的临床效果观察。方法：此次研究的对象是选取2013年3月-2015年6月笔者所在医院收治的难治性免疫性血小板减少患者36例，将所有患者的临床资料进行回顾性分析，并按照随机数字表法分成两组，每组18例，观察组采用免疫球蛋白治疗，对照组采用常规治疗，观察两组患者的治疗效果。结果：经过治疗后，观察组治疗总有效率显著高于对照组，且观察组血小板计数上升幅度高于对照组，观察组血小板上升时间与血小板恢复正常时间均明显少于对照组，差异均有统计学意义（Plt;0.05）。结论：对难治性免疫性血小板减少患者采用免疫球蛋白治疗，可以有效提高治疗有效率，使血小板计数提升，缩短血小板恢复正常时间，治疗效果非常显著，值得临床推广。 【关键词】免疫球蛋白；难治性；免疫性血小板减少；治疗效果 Abstract：Objective：To study the clinical effect of immunoglobulin in the treatment of refractory immune thrombocytopenia.Methods：the research object is selected in 2013 March 2015 June the author admitted to the hospital where the refractory immune thrombocytopenic patients（n = 36），all patients with clinical data were retrospectively analyzed，and divided into two groups according to the random number table method，with 18 cases in each group，the observation group with immune globulin therapy，the control group was treated with conventional therapy，the observation of the therapeutic effect of two groups of patients.Results：after treatment，observation of the treatment group the total efficiency was significantly higher than that of the control group，and the observation group，platelet counts rising range was higher than that of control group，observation group，platelet rise time and platelet recovery time was significantly less than that in the control group，the differences were statistically significant（P lt; 0.05）.Conclusion：of refractory immune thrombocytopenic reduce patients treated with immunoglobulin therapy can effectively improve the efficiency of treatment，the platelet count upgrade，shorten the recovery time of platelet，curative effect is very significant，worthy of clinical promotion. Key words：immunoglobulin；refractory；immune thrombocytopenia；therapeutic effect 现阶段，原发性免疫性血小板减少属于临床上比较常见的疾病之一，根据相关研究结果显示，10%～35%的患者会发展成难治性免疫性血小板减少，主要是由于血小板抗体与细胞免疫介导血小板遭到破坏或者是血小板的生成出现障碍而引起的血小板减少[1]。难治性免疫性血小板减少患者的主要临床表现是存在出血症状以及血小板减少等，成人往往呈现为慢性病程，且大部分患者的病因相对来说比较模糊