瑞芬太尼复合异丙酚-阿曲库胺在鼻内窥镜围手术期应用比较.docVIP

精品论文 参考文献 瑞芬太尼复合异丙酚-阿曲库胺在鼻内窥镜围手术期应用比较 蔡静杏 高晓英 黄晓光 蔡昊（广东潮州市中心医院麻醉科 广东潮州 521000） 【中图分类号】R765.9【文献标识码】A【文章编号】1672-5085（2012）20-0111-02 【摘要】目的 探讨鼻内窥镜术中复合异丙酚-阿曲库胺全静脉麻醉时瑞芬太尼对围手术期的影响。方法 将76例鼻腔内窥镜手术复合异丙酚-阿曲库胺全静脉麻醉患者，采用单盲随机设计，随机分为实验组（R组，n=36）和对照组（F组，n=36）。实验组采用瑞芬太尼先1mu;gmiddot;kg静推，继之以12mu;gmiddot;kgmiddot;h静脉微泵输注。对照组采用芬太尼3mu;gmiddot;kg 静推，继之以2mu;gmiddot;kgmiddot;h静脉微泵输注。比较2组患者围手术期的变化。结果 2组患者一般情况比较，P＞0.05，无统计学差异。R组平均意识消失时间约为（87plusmn;11.6）s， F组平均消失时间（132plusmn;10.3）s；R组围手术期血流动力学反应较F组更稳定；R组清醒时间（209.6plusmn;30.1）s、拔管时间（275.7plusmn;21.4），较F组短，经比较，P＜0.05，有统计学差异。结论 瑞芬太尼复合异丙酚-阿曲库胺起效迅速，恢复快，血流动力学反应稳定。 【关键词】鼻内镜手术 瑞芬太尼 围手术期反应 Remifentanil and propofol ndash; Tracrium in endoscopic sinus Perioperative 【Abstract】　Objectives Nasal endoscope combined withpropofol -Tracrium for total intravenous anesthesia of remifentanil on peri operation period effect.Methods 76 cases of nasal endoscopy operation combined withpropofol -Tracrium total intravenous anesthesia patients,using a single blind randomized design,were randomly divided into experimental group(group R,n=36) and control group(group F,n=36).The experimental group using remifentanil to1mu;gmiddot;kg,followed by12mu;gmiddot;kg middot;hintravenous micro pump infusion.The control group using fentanyl 3mu;gmiddot;kg,followed by 2mu;gmiddot;kg middot;hintravenous micro pump infusion.Note compared 2 groups of patients during operation period of.Results 2 groups of patients in general comparison,P gt; 0.05,no statistically significant differences.R group mean loss of consciousness about (87plusmn;11.6) s,F group mean extinction time of (132plusmn;10.3) s; R group during the operation period ofhemodynamic reSPOnse to a F is more stable; R group awake time (209.6plusmn;30.1) s,extubation time (275.7plusmn;21.4),shorter than that of F group.Comparatively,Plt;0.05,withstatistical difference.Conclusions Remifentanil combined withpropofol -Tracrium and quick,quick recovery,hemodynamic reSPOnse stability. 【Key words】　Na