盐酸多奈哌齐治疗神经衰弱的临床研究.docVIP

精品论文 参考文献 盐酸多奈哌齐治疗神经衰弱的临床研究 王文敏 （中山市大涌医院内科 广东中山 528476） 【摘要】目的 研究分析盐酸多奈哌齐对神经衰弱的临床治疗效果和安全性，以供临床参考和借鉴。方法　选择2010年2月～2012年3月收治的神经衰弱患者70例为临床研究对象，随机将患者分为两组，对照组患者给予临床常规治疗，实验组患者给予盐酸多奈哌齐治疗，对比观察两组患者治疗后的认知功能和生活质量。结果　两组患者治疗前的认知功能和生活质量比较差异不明显，p＞0.05，差异无统计学意义。实验组患者经过我院治疗后，其生活质量和认知功能均优于对照组患者，组间比较差异明显，p＜0.05，差异有统计学意义。结论　使用盐酸多奈哌齐治疗神经衰弱具有较好的效果，可以显著地提高患者的生活质量，值得应用。 【关键词】盐酸多奈哌齐 神经衰弱 认知功能 生活质量 【中图分类号】R453【文献标识码】A【文章编号】2095-1752（2012）36-0175-02 Clinical studies of donepezil hydrochloride in the treatment of neurasthenia. 【Abstract】Objective: To study analysis of donepezil hydrochloride neurasthenia clinical effect and safety, and for clinical reference and learn from. Method: Select February 2010 to March 2012 admitted to the neurological weakness in patients 70 Li clinical research object, randomized the patients divided into two groups, the control group of patients given clinical routine treatment, the experimental group patients given hydrochloric multi Chennai piperazine Qi treatment, comparative observation after treatment, cognitive function and quality of life. Results: cognitive function and quality of life in the two groups of patients before treatment was not significantly different, pgt; 0.05, the difference was not statistically significant. Experimental group after our hospital patients, their quality of life and cognitive function were better than the control group patients, the difference between groups was significantly (p lt;0.05), the difference was statistically significant. Conclusion: The use of donepezil hydrochloride treatment of neurasthenia with good results, can significantly improve the quality of life of patients, it is worth the application. 【Key Words】Donepezil hydrochloride neurasthenia cognitive function quality of life 神经衰弱是临床常见的一种临床综合征，其病因复杂，且多与焦虑和抑郁症状并存，因此在临床多给予抗焦虑和抗抑郁方法治疗，但是效果并不理想[1.2]。而随着疾病的严重程度加重，导致疾病迁延，病程长，患者生活质量严重降低。而如何更好地提高患者的治疗效果，提高患者生活质量十分重要。我院在临床工作中采用盐酸多奈哌齐治疗神经衰弱，取得了较好的效果，报告如下： 1 资料与方法