双探针冷冻手术中冻结过程相变传热的数值模拟研究.pdfVIP

中国工程热物理学会 传热传质学 学术会议论文 编号：083171 双探针冷冻手术中冻结过程相变传热的 数值模拟* 赵芳 陈振乾 施明恒+ （东南大学能源与环境学院，南京 210096） （Tel: 025 +Email: zqchen@seu.edu.cn ） 摘要：建立了生物组织(含正常组织与肿瘤)冻结过程相变传热的数学模型，对生物组织在同时插入两 根探针时冻结过程中温度场分布及冰晶生长规律进行了模拟。模型中采用树状分形方法模拟血管的结 构形态，同时考虑了组织在冻结过程中存在冻结区、糊状区和未冻结区三个区域。模拟结果表明：在 冷冻初期，冰晶的生长速度较快，到了后期冰晶生长速度明显减慢；探针间距仅仅在冷冻初期对冰晶 生长产生影响，随着冷冻时间的增加这种差别会逐渐减少甚至消失。 关键词：生物组织 冷冻 相变 分形 Numerical simulation of freezing phase change heat transfer process in cryosurgery with two cryoprobes Zhao Fang Chen Zhenqian Shi Mingheng （School of Energy and Environment, Southeast University, Nanjing 210096, China ） Abstract: A heat transfer model of freezing phase change in biological tissue (including normal biological tissue and tumor) was established. Temperature distribution and ice crystal growth process of biological tissue embedded two cryoprobes were numerical simulated during the freezing process. The tree-like branched fractal method was applied for simulating the structure of blood vessels, while the differences of frozen, phase-changing and unfrozen regions during the freezing process of biological tissue were also considered in the model. The simulation results showed that the growth rate of ice crystal in the initial freezing period was larger than that in later period; while the influence of the placement distance of two cryoprobes for growth of ice crystal was evident just during the initial freezing phase, and the distinction of ice crystal growth which resulted from different distance of two cryoprobes decreased gradually with increasing of freezing time. Keywords: biological tissue; freezing; ph