米非司酮治疗子宫肌瘤临床疗效评价.docVIP

精品论文 参考文献 米非司酮治疗子宫肌瘤临床疗效评价 卢潭敏 路炜 [摘 要]目的：探讨米非司酮治疗子宫肌瘤的临床效果。方法：收集我院2011年11月-2012年12月期间诊治的子宫肌瘤患者84例作为研究对象，对患者应用米非司酮治疗，回顾性分析患者的临床资料，观察治疗效果。结果：研究结果显示，本组患者经米非司酮治疗后取得了良好的临床效果，治疗前子宫平均体积为（329.69plusmn;18.23）cmsup3;，子宫肌瘤体积为（91.36plusmn;11.27）cmsup3;，卵泡刺激素为（24.85plusmn;2.28）mIU/L，黄体生成素为（21.96plusmn;2.13）mIU/L、雌二醇为（385.14plusmn;26.73）pg/mL，血红蛋白为（79.35plusmn;6.62）g/L，治疗后子宫平均体积为（221.17plusmn;19.55）cmsup3;，子宫肌瘤体积为（37.48plusmn;3.84）cmsup3;，卵泡刺激素为（14.99plusmn;1.78）mIU/L，黄体生成素为（12.89plusmn;1.42）mIU/L、雌二醇为（155.12plusmn;16.44）pg/mL，血红蛋白为（124.17plusmn;15.62）g/L，患者治疗前后子宫肌瘤体积、卵泡刺激素、黄体生成素、雌二醇、血红蛋白水平比较具有明显差异(Plt;0．05)。同时，本组患者中有19名患者出现不良反应，包括10例头晕，9例恶心，均为轻度，患者耐受，不良反应发生率为22.62%。结论：米非司酮治疗子宫肌瘤具有良好的临床疗效，能有效促进子宫肌瘤体积、雌二醇、卵泡刺激素、血红蛋白、黄体生成素水平改善，且不会引起明显不良反应，值得在临床应用上推广。 [关键词]米非司酮 子宫肌瘤 临床效果 DOI:10.3760/cma.j.issn.0376-2491.2014.44.008 作者单位：252002 山东聊城，山东省聊城市人民医院妇产科 The Clinical Effect of Mifepristone for Uterine Fibroids Lu Tanmin, Lu Wei Abstract: Objective to study the clinical effect of Mifepristone treatment for uterine fibroids. Methods 84 patients with uterine fibroids from November 2011 to December 2012 in the authorsrsquo; hospital were collected as the research object and given Mifepristone treatment. The clinical treatment effect was retrospectively analyzed. Results The patients accepted Mifepristone treatment achieved good clinical effect: before the treatment, the average volume of uterus is (329.69 + 18.23) cm, uterine fibroid volume is (91.36 + 11.27) cm, follicle-stimulating hormone is (24.85 2.28 mm) mIU/L, luteinizing hormone is (21.96-2.13) mIU/L, estradiol is (385.14 26.73 mm) pg/mL, hemoglobin is (79.35-6.62) g/L; after the treatment, average volume uterine is (221.17 + 19.55)cm, uterine fibroid volume is (37.48 + 3.84)cm, follicle-stimulating hormone is (14.99 1.78 mm) mIU/L, luteinizing hormone is (12.89-1.42) mIU/L, estradiol is (155.12 16.44 mm) pg/mL, hemoglobin is (124.17-15.62) g/L. There are obvious differences