老年慢性阻塞性肺疾病急性加重患者有创机械通气撤机失败危险因素分析.docVIP

精品论文 参考文献 老年慢性阻塞性肺疾病急性加重患者有创机械通气撤机失败危险因素分析 娄底市娄星区妇幼保健院 湖南娄底 417000 【摘 要】 目的 探讨老年慢性阻塞性肺疾病（COPD）急性加重期患者有创机械通气撤机失败危险因素，为降低撤机失败发生率提供临床依据。方法 收集2013 年1 月至2015 年1 月我院收治的老年COPD急性加重期患者100 例，所有患者均接受有效机械通气治疗，依据患者撤机结果分为两组，其中39 例患者撤机失败，作为观察组，61 例患者撤机成功，作为对照组，对两组患者的临床资料进行回顾性分析。结果 两组患者在MODS发生率、机械通气时间和心力衰竭发生率方面组间差异具有极显著性差异，Plt;0.01。结论 MODS、机械通气时间过长、心力衰竭是可能导致老年COPD急性加重期患者有创机械通气撤机失败的高危因素，临床治疗中对存在上述体征的患者应予以高度关注，合理评价患者的治疗风险，最大程度的降低机械通气撤机失败的发生。 【关键词】老年；慢性阻塞性肺病；急性加重期；撤机失败；危险因素 【Abstract 】 objective to investigate the elderly with chronic obstructive pulmonary disease（COPD）in acute aggravating period of invasive mechanical ventilation in patients with ventilator failure risk factors，to reduce the incidence of ventilator failed to provide clinical basis.Methods between January 2013 and January 2013 of our hospital 100 cases of senile COPD patients with acute aggravating period，all patients were treated with effective mechanical ventilation，according to the results of patients with ventilator，divided into two groups，including 39 patients withdraw machine failure，as the observation group，61 cases of patients with ventilator is successful，as control group，the clinical data of two groups of patients were retrospectively analyzed.Results two groups of patients in the incidence of MODS，mechanical ventilation time and the incidence of heart failure group were extremely significant differences between differences，P lt; 0.01）.Conclusion MODS，mechanical ventilation time is too long，is can lead to heart failure in elderly patients with COPD exacerbations period of invasive mechanical ventilation withdraw machine failure risk factors，clinical signs and treatment of the existence of high attention must be paid to the patients，the treatment of patients with reasonable evaluation risk，the greatest degree of reduce mechanical ventilation withdraw machine failure occurred. 【Key words 】 the elderly；Chronic obstructive pulmonary disease（copd）；Acute exacerbation period；Withdraw machine failure；Risk factor