肃降肺胃法治疗胃食管反流性咳嗽的临床观察.docVIP

精品论文 参考文献 肃降肺胃法治疗胃食管反流性咳嗽的临床观察 杨大坚1 管奕婷2 车彦贞3 　　（广东省佛山市佛平路40号 广东 佛山 528200） 　　【摘 要】目的：本课题以中医理论为指导，观察并探讨肃降肺胃法治疗胃食管反流性咳嗽的临床疗效。方法：以60例胃食管反流性咳嗽患者为研究对象，采用前瞻性、随机、对照的研究方案，将研究对象分为对照组30例和治疗组30例，对照组给予奥美拉唑及多潘立酮治疗，治疗组给予肃降肺胃中药治疗。根据本病的中医证候特点，将咳嗽、咯痰等主症作为观察指标，制定评分标准，观察两组临床疗效，治疗前后的症状、体征、不良反应和复发情况，并用SPSS15.0统计软件进行数据分析。结果：1.临床疗效：治疗组总有效率为93.33%，对照组总有效率为66.67%。两组疗效对比，具有显著性差异(Plt;0.05)，提示治疗组的疗效明显优于对照组。2.临床症状：两组患者治疗后的临床症状改善较治疗前有显著性差异(Plt;0.05)。治疗组治疗后在咳嗽、咯痰、泛酸、嗳气、胸骨后灼热感等指标改善明显，与对照组比较，有显著性差异(Plt;0.05)。说明两组治疗都可以改善患者的临床症状，但治疗组疗效优于对照组。结论：运用肃降肺胃中药治疗胃食管反流性咳嗽，临床疗效确切，能改善患者多种临床症状，复发率低，无毒副作用。 　　【关键词】胃食管反流性咳嗽；肃降肺胃法；中医；中药；临床研究 　　【中图分类号】R259 【文献标识码】B 【文章编号】1003-5028（2015）6-0478-02 　　【Abstract】Objective：Guided by Chinese medicine theory, this topic is to observe and discuss the clinical effect of the method of clearing and descending lungs and stomach for the treatment of Gastroesophageal reflux-related chronic cough.Methods：Taking Gastroesophageal reflux-related chronic cough patients as the research object, adopting the research program of prospective random control study, 60 patients were randomly divided into a treatment group and a control group, with 30 cases in each group. The treatment group was treated by the method of clearing and descending lungs and stomach and the control group was treated with omeprazole and domperidone. According to TCM syndromes of the disease, cough, expectoration and other main symptoms as outcome measures, the development of rating standards, clinical efficacy, before and after treatment of the symptoms, signs, adverse reactions and recurrence with SPSS15.0 statistical software for data analysis.Results：1.Clinical curative effect: the total effective rate was 93.33% in the treatment group and 66.67% in the control group, with a significant difference between the two groups (Plt;0.05). It suggests that the curative effects in the treatment group were better, compared to the control group. 2.Clinical symptom: the symptoms of two groups improved dramaticall