自拟接骨方辅助手术对肱骨髁上髁间骨折术后患者康复效果及IGF-Ⅰ、BMP-2的改善研究.docVIP

精品论文 参考文献 自拟接骨方辅助手术对肱骨髁上髁间骨折术后患者康复效果及IGF-Ⅰ、BMP-2的改善研究 刘琦 [摘 要]目的 自拟接骨方辅助手术对肱骨髁上髁间骨折术后患者康复效果及IGF-Ⅰ、BMP-2的改善研究。方法 选取我院2010年1月至2011年1月92肱骨髁上髁间骨折患者为研究对象，将患者抽签随机分为观察组与对照组，每组46例。对照组采用切开复位内固定术治疗，观察组在对照组的基础上另行自拟接骨方干预，比较两组中医症候评分，肘关节功能优良率，血清胰岛素样生长因子（IGF-Ⅰ）、骨形态发生蛋白（BMP-2）水平及并发症发生率。结果 两组治疗前中医症候评分比较无统计学意义（Pgt;0.05）；观察组疼痛、肿胀、瘀斑、口渴、尿赤，便秘等中医症候评分均低于对照组，有统计学意义（Plt;0.05)。观察组肘关节功能优良率95.65%高于对照组76.09%，有统计学意义（Plt;0.05)。治疗后，观察组IGF-Ⅰ水平（9.36plusmn;2.63）rho;/mu;g#9642;L-1、BMP-2水平（90.05plusmn;8.65）rho;/ng#9642;L-1高于对照组（6.58plusmn;2.24）rho;/mu;g#9642;L-1、（73.26plusmn;8.12），有统计学意义（Plt;0.05)。观察组并发症发生率2.17%低于对照组15.22%，有统计学意义（Plt;0.05)。结论 自拟接骨方辅助手术治疗肱骨髁上髁间骨折效果显著，可有效改善患者临床症状，提高IGF-Ⅰ和BMP-2水平，减少并发症。 [关键词]自拟接骨方 手术 肱骨髁上髁间骨折 康复效果 IGF-Ⅰ BMP-2 DOI:10.3760/cma.j.issn.0376-2491.2016.28.22 作者单位：610000，四川成都，核工业四一六医院 The self-made bone party auxiliary surgery to improve the rehabilitation effect of IGF-, BMP-2 and 1 of humeral intercondylar fracture after operation Liu Qi Abstract：Objective: The self-made bone party auxiliary surgery to improve the rehabilitation effect of IGF-, BMP-2 and 1 of humeral intercondylar fracture after operation.Methods:Selected in our hospital from 2010 January to 2011 January 92 humeral intercondylar fracture patients as the research object, the patients were randomly divided into observation group and control group, 46 cases in each group. The control group was treated with open reduction and internal fixation for the treatment of, the observation group on the basis of the control group separately self-made jiegufang intervention, compared two groups of TCM syndrome score, the excellent and good rate of the elbow joint function and serum insulin like growth factor (IGF), bone morphogenetic occurred protein (BMP-2) levels and the incidence of complications. Results: The two groups before treatment symptom score of traditional Chinese medicine is no statistical significance (P gt; 0.05); observation group pain, swelling, petechia, thirsty, red urine, constipation, etc