贵州省2014年疑似预防接种异常反应监测分析.docVIP

精品论文 参考文献 贵州省2014年疑似预防接种异常反应监测分析 徐飞 张大勇 杜雯 张丽 冯军 　　（贵州省疾病预防控制中心免疫规划所 贵州贵阳 550004） 　　【摘要】 目的：分析2014年贵州省疑似预防接种异常反应（AEFI）的发生特征，对AEFI监测系统运转情况、预防接种安全性进行评价。方法：通过AEFI监测系统收集贵州省2014年1月1日至2014年12月31日报告的AEFI个案数据，通过描述性方法对相关指标进行流行病学分析。结果：贵州省2014年共报告AEFI个案261例，报告县覆盖率为87.1%，48h内报告率为90.42％，48h内调查率为94.59％，3日内调查表上传率为72.97%。AEFI报告发生率为1.68/10万剂，严重AEFI报告发生率为0.07/10万剂，异常反应报告发生率为0.12/10万剂。AEFI病例中男女比例为1.66：1；le;1岁占61.3%；病例发生集中在第二季度；治愈和好转病例占90.42%。异常反应报告发生率最高的是无细胞百白破疫苗（0.34/10万剂），异常反应中临床症状报告发生率居前三位的是其他（0.4/10万剂）、过敏性皮疹（0.15/10万剂）和无菌性脓肿（0.01/10万剂）。结论：贵州省AEFI监测敏感性和完整性都有所提升，但同发达地区相比，仍存在较大差距。需通过提升业务人员素质、建立合理的考核机制、强化非NIP疫苗监测报告管理等措施不断提高AEFI监测水平。 　　【关键词】疑似预防接种异常反应；监测 　　【中图分类号】R18 【文献标识码】A 【文章编号】1007-8231（2016）10-0008-03 　　Study on the Surveillance of Adverse Events Following Immunization of Guizhou Province in 2014 　　Xu Fei,Zhang Dayong,Du Wen,Zhang Li,Feng Jun . 　　Center for Disease Control and Prevention of Guizhou,Guiyang 550004,China 　　【Abstract】Objective To analyze occurrence features of adverse events following immunization(AEFI) and evaluate the operating quality of AEFI information management system and the immunization safety in Guizhou Province in 2014.Method AEFI data reported from January 1,2014 to December 31,2014 were collected through the National AEFI Information Management System.The descriptive method was used to analyze the AEFI occurrence features.Results 261 cases of AEFI were reported in 2014,the proportion of counties with reporting was 87.1%,Proportion of cases reported within 48h was90.42%,and the proportion of cases investigated within 48h was 94.59%, questionnaire upload rate in 3 days was 72.97%.AEFI reported incidence rate was 1.68 per 100,000 doses, Serious AEFI reported incidence rate was 0.07 per 100,000 doses, Abnormal reaction reported incidence rate was 0.12 per 100,000 doses.The ratio of male-female was 1.66：1；Cases le;1 year old accounted for 61.3%；The cases were occurred mostly in second quarter,and 90.42% cases