第七章 突变试题.doc

第七章 突变 一 选择题 1. A mutation changes a GC base pair to an AT base pair. This is a ___ mutation. A? transversion ? B? transition C? transpositional D? translocation 2. A mutation changes an AT base pair to TA. This is a ___ mutation ? A? transversion B? transition C? transpositional D? translocation 3. Which of the following is an example of a nonsense mutation? A? ACG to ACC B? AUG to UUG ?C? UAC to UAG D? AAA to UUU 4. A mutation changes a codon for leucine into one that signifies isoleucine. This is a ___ mutation. A? nonsense ? B? missense C? lethal D? neutral 5. A mutation occurs in which an AUU codon is changed to an AUC codon. Both of these codons signify the amino acid leucine. This is a ___ mutation. A? nonsense B? missense ?C? silent D? neutral 6. A mutation occurs in which an AAA codon, which signifies lysine, into AGA which signifies a chemically similar amino acid arginine. This is an example of a ___ mutation. A? nonsense B? missense C? silent ? D? neutral 7. A ___ mutation may result from the insertion or deletion of a nucleotide. A? nonsense B? missense ?C? frameshift D? neutral 8. A ___ mutation in a gene in amino acid biosynthesis pathway permits the bacterium to once again synthesize the amino acid. ? A? reversion B? missense C? neutral D? frameshift 9. In E. coli, suppressor mutations are often located in genes for A? metabolic enzymes B? promoters ? C? tRNA genes D? DNA polymerase. 10. Which type of mutation may occur spontaneously in cells? A? deamination B? depurination C? depyrimidination ? D? all of the above 11. Which of the following agents may induce mutations in DNA? A? ultraviolet radiation B? gamma radiation C? 5-bromouracil ?D? all of the above 12. The mutation induced most commonly in DNA treated with ultraviolet light is the result of A? a base substitution ?B? creation of thymine dimmers C? a tautomeric shift D? deamination of a base 13. 5-bromouracil is an analog of which base? ?A? thymine B? uracil C? cytosine D? adenine 1