高压氧或鼓室内激素对突发性聋的挽救治疗疗效对比.docVIP

精品论文 参考文献 高压氧或鼓室内激素对突发性聋的挽救治疗疗效对比 杨立 何刚 唐子轩 黄红星 　　（遂宁市中心医院耳鼻喉-头颈外科 629000） 　　【摘要】目的 了解高压氧或鼓室内激素对入院治疗超过1周无效的中度以上突发性聋患者的治疗价值。方法 对56例收入院治疗1周无效的中度以上突发性聋患者临床资料进行回顾性分析。经激素、改善微循环、营养神经等药物治疗治疗1周无效的患者，根据患者意愿分为鼓室内激素注射治疗组和高压氧治疗组，继续使用改善微循环、营养神经等药物，对两组的短期预后进行比较。结果 经使用高压氧或鼓室内激素治疗1周，高压氧组平均听力改善12.7plusmn;18.0 dB，鼓室内激素组听力改善 13.6plusmn;16.5 dB,两组间平均听阈改善差异无统计学差异（t=0.2，pgt;0.05）。高压氧组治疗有效率为45.2 %，鼓室内激素组治疗有效率为48.0 %，组间疗效差异无统计学意义（mu;=0.54，pgt;0.05）。发病到开始使用时间7～14天、15～30天、30天以上有效率分别为54.5%、26.7%、37%，组间疗效差异有统计学意义（mu;=6.52，plt;0.05），所有患者均未出现严重并发症。结论 高压氧与鼓室内激素对入院治疗超过1周无效的中度以上突发性聋有治疗意义,两种治疗短期疗效无明显差异，可根据具体情况选择治疗方案。 　　【关键词】听力丧失 突发性 高压氧 鼓室内激素 　　【中图分类号】R764.43+7 【文献标识码】A 【文章编号】2095-1752（2014）22-0033-02 　　Effectiveness of hyperbaric oxygen therapy or intratympanic dexamethasone treatment for salvage therapy of sudden sensorineural hearing loss 　　Yang Li,He Gang,Tang Zi-xuan,Huang Hong-xing 　　Suining Central Hospital,Suining 62900，Sichuan China 　　【Abstract】Objective: To investigate and analyze the significance of hyperbaric oxygen therapy or intratympanic dexamethasone treatment for sudden sensorineural hearing loss which is no respect for one weekrsquo;s treatment.Methods:We retrospectived 56 patients with sudden sensorineural hearing loss(SSNHL) who pure tone average(PTA) threshold was more than 40 dB and were admitted to the department of Otorhinolarngology-Head and Neck Surgery,The Suining Central Hospital from January 2010 to January 2013,and they were no respected for one weekrsquo;s treatment. All of the patient were trearted with glucocorticoids, thrombolytic, and used hyperbaric oxygen therapy or intratympanic dexamethasone as remedial treatment. Analyzed the PTA after one week treatment.Results:After cure ,the PTA threshold improvement of hyperbaric oxygen therapy or intratympanic dexamethasone were separately 12.7plusmn;18.0 dB,13.6plusmn;16.5 dB,which were no significantly different in two groups(t=0.2,pgt;0.05). The efficient in