药物合成6氧化反应.ppt

Chapter 6 Oxidation;What is Oxidation;What is Oxidation Oxidation is the conversion of a functional group in a molecule to a higher category;The Mechanism of Oxidation;1.Direct electron transfer;2.Hydride transfer;Oxidations of Alkyl-compounds;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;1.oxidations of alkyl in benzyl;2.oxidations of α-alkyl in carbonylcompounds;2.oxidations of α-alkyl in carbonylcompounds;2.oxidations of α-alkyl in carbonylcompounds;2.oxidations of α-alkyl in carbonylcompounds;2.oxidations of α-alkyl in carbonylcompounds;3. Oxidations of Alkyl in allyl;3. Oxidations of Alkyl in allyl;3. Oxidations of Alkyl in allyl;3. Oxidations of Alkyl in allyl;3. Oxidations of Alkyl in allyl;3. Oxidations of Alkyl in allyl;Oxidations of Alcohol;Oxidations of Alcohol;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;1.Formation of carbonyl compounds;2.Formation of carbonic acids;3.Oxidations of 1,2-diol;3.Oxidations of 1,2-diol;3.Oxidations of 1,2-diol;Oxidations of C-C double bond;Oxidations of C-C double bond;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;1.Formation of epoxy compound;2.forma