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ADVANCES IN CLINICAL CHEMISTRY, VOL. 48
FETAL SKIN WOUND HEALING
Edward P. Buchanan,*,1 Michael T. Longaker,†
and H. Peter Lorenz†
*Division Plastic Surgery, Department of Surgery, Stanford
University School of Medicine, Stanford, California 94305, USA
†Division Plastic Surgery, Department of Surgery, Pediatric
Surgical Research Laboratory, Stanford University School of
Medicine, Stanford, California 94305‐5148, USA
1. Abstract. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138
2. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138
3. Development . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140
3.1. Fetal Skin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140
3.2. Fetal ECM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140
3.3. Collagen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 140
3.4. Hyaluronic Acid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
3.5. Proteoglycan ECM Modulators. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 141
4. Scarless Fetal Wound Repair Specificity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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