Human ESC derived Neural Rosettes and Neural Stem Cell Progression英文文献.pdfVIP

Human ESC derived Neural Rosettes and Neural Stem Cell Progression英文文献.pdf

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Downloaded from on October 22, 2010 - Published by Cold Spring Harbor Laboratory Press Human ESC-derived Neural Rosettes and Neural Stem Cell Progression Y. Elkabetz and L. Studer Cold Spring Harb Symp Quant Biol 2008 73: 377-387 originally published online February 9, 2009 Access the most recent version at doi: 10.1101/sqb.2008.73.052 References This article cites 119 articles, 42 of which can be accessed free at: /content/73/377.refs.html Article cited in: /content/73/377#related-urls Email alerting Receive free email alerts when new articles cite this article - sign up in the box at the service top right corner of the article or click here To subscribe to Cold Spring Harbor Symposia on Quantitative Biology go to: /subscriptions Copyright © 2008, Cold Spring Harbor Laboratory Press Downloaded from on October 22, 2010 - Published by Cold Spring Harbor Laboratory Press Human ESC-derived Neural Rosettes and Neural Stem Cell Progression Y. ELKABETZ AND L. STUDER Developmental Biology Program, Division of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10065 Neural stem cells (NSCs) are defined by their ability to self-renew while retaining differentiation potential toward the three main central nervous system (CNS) lineages: neurons, astrocytes, and oligodendrocytes. A less appreciated fact about isolated NSCs is their narrow repertoire for generating specific neuron types, which are generally limited to a few region-specific sub- types such as GABAergic and glutamatergic neurons. Recent studies

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