Cone beam computed tomography with a flat panel imager Initial performance characterization英文文献.pdfVIP
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Cone-beam computed tomography with a flat-panel imager: Initial
performance characterization
D. A. Jaffraya) and J. H. Siewerdsen
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073
Received 15 September 1999; accepted for publication 29 March 2000
The development and performance of a system for x-ray cone-beam computed tomography CBCT
using an indirect-detection flat-panel imager FPI is presented. Developed as a bench-top prototype
for initial investigation of FPI-based CBCT for bone and soft-tissue localization in radiotherapy, the
system provides fully three-dimensional volumetric image data from projections acquired during a
single rotation. The system employs a 512512 active matrix of a -Si:H thin-film transistors and
photodiodes in combination with a luminescent phosphor. Tomographic imaging performance is
quantified in terms of response uniformity, response linearity, voxel noise, noise-power spectrum
NPS, and modulation transfer function MTF, each in comparison to the performance measured
on a conventional CT scanner. For the geometry employed and the objects considered, response is
uniform to within 2% and linear within 1%. Voxel noise, at a level of 20 HU, is comparable to
the conventional CT scanner. NPS and MTF results highlight the frequency-dependent transfer
characteristics, confirming that the CBCT system can provide high spatial resolution and does not
suffer greatly from additive noise levels. For larger objects and/or low exposures, additive noise
levels must be reduced to maintain high performance. Imaging studies of a low-contrast phantom
and a small animal a euthanized rat qualitatively demonstrate excellent soft-tissue visibility and
high spatial resolution. Image qualit
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