Cone beam computed tomography with a flat panel imager Initial performance characterization英文文献.pdfVIP

Cone beam computed tomography with a flat panel imager Initial performance characterization英文文献.pdf

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Cone-beam computed tomography with a flat-panel imager: Initial performance characterization D. A. Jaffraya) and J. H. Siewerdsen Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan 48073 Received 15 September 1999; accepted for publication 29 March 2000 The development and performance of a system for x-ray cone-beam computed tomography CBCT using an indirect-detection flat-panel imager FPI is presented. Developed as a bench-top prototype for initial investigation of FPI-based CBCT for bone and soft-tissue localization in radiotherapy, the system provides fully three-dimensional volumetric image data from projections acquired during a single rotation. The system employs a 512512 active matrix of a -Si:H thin-film transistors and photodiodes in combination with a luminescent phosphor. Tomographic imaging performance is quantified in terms of response uniformity, response linearity, voxel noise, noise-power spectrum NPS, and modulation transfer function MTF, each in comparison to the performance measured on a conventional CT scanner. For the geometry employed and the objects considered, response is uniform to within 2% and linear within 1%. Voxel noise, at a level of 20 HU, is comparable to the conventional CT scanner. NPS and MTF results highlight the frequency-dependent transfer characteristics, confirming that the CBCT system can provide high spatial resolution and does not suffer greatly from additive noise levels. For larger objects and/or low exposures, additive noise levels must be reduced to maintain high performance. Imaging studies of a low-contrast phantom and a small animal a euthanized rat qualitatively demonstrate excellent soft-tissue visibility and high spatial resolution. Image qualit

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